SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Structure |
| Discussion Leader: Wah Chiu (Baylor College of Medicine) |
7:40 pm - 8:10 pm | Michael G. Rossmann (Purdue University)
"Using antibodies to track conformational changes of flaviviruses" |
8:10 pm - 8:25 pm | Discussion |
8:25 pm - 8:55 pm | Grant Jensen (California Institute of Technology)
"Electron cryotomographic studies of HIV-1 maturation" |
8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Poster Talk: Yizhi Tao (Rice U.)
"Unique capsid organization of a dsRNA virus revises the model for capsid assembly" |
9:20 pm - 9:30 pm | Poster Talk: Xiangan Liu (Baylor College of Medicine)
"Cryo-EM Reveals the Structure of the Capsid Protein and Symmetry Mismatch of the Portal Vertex in Cyanophage P-SSP7" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Physical and mechanical properties of supra-molecular structures |
| Discussion Leader: Charles Knobler (University of California - Los Angeles) |
9:00 am - 9:35 am | Gijs Wuite (Vrije Univ, Netherlands)
"Exploring the nano-mechanics of viruses" |
9:35 am - 9:50 am | Discussion |
9:50 am - 10:00 am | Poster Talk: Carolina Carrasco Pulido (Universidad Autonoma de Madrid)
"Tailoring of the mechanical properties of a virus by protein engineering" |
10:00 am | Coffee Break / Group Photo |
10:30 am - 11:05 am | Roya Zandi (University of California - Riverside)
"Nonequilibrium growth, retrovirus assembly and conical structures" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Rob Phillips (California Institute of Technology)
"How Viruses Make New Viruses: A Single Molecule View" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Poster Talk: Ian Molineux (University of Texas)
"Studies on the mechanisms used in vivo for phage DNA ejection into the infected cell" |
12:20 pm - 12:30 pm | Poster Talk: Siyang Sun (Purdue University)
"The Structure of the Phage T4 DNA packaging Motor Suggests a Mechanism Dependent on Electrostatic Forces" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of self-assembly |
| Discussion Leader: Peter Prevelige (University of Alabama - Birmingham) |
7:30 pm - 8:05 pm | Carlos Catalano (University of Washington)
"Assembly and Maturation of the Lambda Procapsid" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:55 pm | Stephen Granick (University of Illinois - Urbana Champaign)
"Self-assembly: nanoparticles, phospholipids, colloids" |
8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Poster Talk: Laura Palomares (Universidad Nacional Autonoma de Mexico)
"Assembly kinetics of rotavirus VP6: From tubes to icosahedral structures" |
9:20 pm - 9:30 pm | Poster Talk: Alan Rein (National Cancer Institute)
"On the Role of RNA in retrovirus particle structure" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Theoretical properties of regular structures and their assembly |
| Discussion Leader: Charles L. Brooks III (University of Michigan) |
9:00 am - 9:10 am | Introduction |
9:10 am - 9:45 am | William Klug (University of California - Los Angeles)
"Structural mechanics of viral shells: stretching continuum models to their limits" |
9:45 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Michael Hagan (Brandeis University)
"From solid nanoparticles to flexible polyanions -- the role of the packaged cargo in capsid assembly" |
11:00 am - 11:15 am | Discussion |
11:15 am - 11:45 am | Reidun Twarock (University of York, UK)
"Hidden symmetries in virus architecture and their implications for structural transitions and function" |
11:45 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Poster Talk: Alain Mermet (University Lyon 1)
"Collective vibrational modes of viruses" |
12:10 pm - 12:20 pm | Poster Talk: Michael Widom (Carnegie Mellon University)
"Capsid faceting as a soft-mode transition" |
12:20 pm - 12:30 pm | Poster Talk: Xiangyun Qiu (National Institutes of Health)
"Charting the Structure and Energetics of Packaged DNA in Bacteriophages" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Dynamical properties of viruses |
| Discussion Leader: Peter Stockley (University of Leeds, UK) |
7:30 pm - 8:05 pm | John E. Johnson (Scripps Research Institute)
"Unexpected twists in virus maturation: how bacteriophage subunits shape an energy landscape" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:55 pm | Max Nibert (Harvard University)
"Peptide release for membrane penetration by reovirus" |
8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Poster Talk: Yorgo Modis (Yale University)
"Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion" |
9:20 pm - 9:30 pm | Poster Talk: Deborah Kuzmanovic (University of Michigan)
"Structural analysis of the phage MS2 components using Small Angle Neutron Scattering" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Bio-inorganic virus-based materials: electronics / photonics / catalysis |
| Discussion Leader: David Evans (John Innes Institute, UK) |
9:00 am - 9:40 am | Trevor Douglas (Montana State University)
"Capsids for synthetic encapsulation: polymers, molecules and nanosolids" |
9:40 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Jeroen Cornelissen (Radboud University, Netherlands)
"Viruses as supramolecular containers and scaffolds" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Matt Francis (University of California - Berkeley)
"Building new materials from synthetically modified viral capsids" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Poster Talk: Stella Aniagyei (Indiana University)
"Towards targeted delivery of the anti-cancer drug cisplatin using virus-based platforms" |
12:20 pm - 12:30 pm | Poster Talk: Harry Bermudez (Umass)
"Functionality in bacteriophages: using asymmetry to add responsiveness" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Biomedical approaches based on virus structure and properties |
| Discussion Leader: Mavis Agbandje-McKenna (University of Florida) |
7:30 pm - 8:05 pm | Marianne Manchester (Scripps Research Institute)
"Exploiting the natural properties of viral nanoparticles for biomedical therapeutics" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:55 pm | Robert L. Garcea (University of Colorado - Boulder)
"The Structural Biology of Papillomaviruses in Relation to Vaccine Development" |
8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Poster Talk: Chris Broomell (Montana State University)
"Enhancement of protection against respiratory infection following treatment with protein cage nanoparticles" |
9:20 pm - 9:30 pm | Poster Talk: Aravind Asokan (University of North Carolina at Chapel Hill)
"Engineering new viral tropisms by rational manipulation of capsid surface topology" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 12:30 pm | Connecting nano to mesoscale, metamaterials |
| Discussion Leader: M.G. Finn (Scripps Research Institute) |
9:00 am - 9:40 am | Samuel Stupp (Northwestern University)
"Self-Assembly of Virus Mimics and Hierarchical Structures" |
9:40 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 11:05 am | Sharon Glotzer (University of Michigan)
"Relating Building Block Shape and Complexity for Assembly" |
11:05 am - 11:20 am | Discussion |
11:20 am - 11:55 am | Ichiro Yamashita (Matsushita Electronics, Japan)
"Nanodevice fabrication using protein supramolecule and biomineralization" |
11:55 am - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Poster Talk: Christoph Schmidt (Georg-August-Universitaet)
"Shell mechanics of viral capsids" |
12:20 pm - 12:30 pm | Poster Talk: Mime Kobayashi (NAIST)
"Fabrication of nano-scaled structures using genetically engineered tobacco mosaic virus" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | The next step / late breaking results |
| Discussion Leader: Mark J. Young (Montana State University) |
7:30 pm - 8:05 pm | Otto Sankey / Kong-Thon Tsen (Arizona State University)
"Simulations and theory of virus inactivation by driving mechanical motion with ultra-fast light pulses" |
8:05 pm - 8:20 pm | Discussion |
8:20 pm - 8:55 pm | Seung-Wuk Lee (University of California - Berkeley)
"Genetically Engineered Viruses for Tissue Regenerating Materials" |
8:55 pm - 9:10 pm | Discussion |
9:10 pm - 9:20 pm | Closing Short Talk: Brian Bothner (Montana State Univeristy)
"Stability and Dynamics of Protein Cages from an Extremophile" |
9:20 pm - 9:30 pm | Closing Short Talk: Roger Hendrix (University of Pittsburgh) |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |