Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Virus Assembly: Theory and Practice
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:25 pm
"Virion-Based Therapeutics: Small Molecules Affect Virus Structure and Dynamics"
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:15 pm
"Nano-Reactor Assembly Across Multiple Length Scales"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Plant Virus-Based Therapeutics and Contrast Agents"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Viral Capsids for Drug Delivery and 3-D Nanomaterial Construction"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Tobacco Mosaic Virusbased Biosensors"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Viral and Microbial Elements as Building Blocks for Nanobiosensor Platform"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Cell-Surface Mimics to Probe Interactions Between Herpes Simplex Viruses and Cell-Surface Carbohydrates"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Development of Functional Nano-Building Blocks and Nano-Reaction Clusters"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Reshaping Oncolytic Reovirus for the Tumor Niche"
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:10 pm
"Viruses as Oncolytic Agents: Preclinical and Clinical Insights"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:45 pm
"Engineering AAV Vectors for Clinical Application"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Structural Studies of
Viruses
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Structural Virotechnology or How 3D Cryo-EM Facilitates Viral Biotechnology"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Structural Analysis of Herpes Virus Infection"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Virotrap: Abducting Protein Complexes from Mammalian Cells"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Viral RNA Genomes by CryoEM: Atomic Structures and Mechanisms of Action"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"Flying Viruses - From Biophysical to Structural Characterization"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Assembling Enzymatic Cascade Inside Virus-Based Nanocompartments Using Dual-Tasking Nucleic Acid Tags"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:30 pm
"An Engineering Approach to Probing Host-Pathogen Interactions Using Single Virion Tracking Microscopy"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Polymer Based Protein Engineering Using Viral Nanoparticles"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Stability and Structure of True-Type AAV2 Correlated to Improved Neuronal Transduction"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Capsid Assembly and Stabilization by Decoration Proteins"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Assembly and Biomechanics of Viruses
Session in memory of Dr. William Klug.
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:45 am
"Some New Twists on CCMV Self-Assembly, 50 Years After Bancroft"
9:45 am - 9:55 am
Discussion
9:55 am - 10:20 am
"Genome Encapsidation and Release"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"In Vitro Protease Cleavage and Computer Simulations Reveal the HIV-1 Capsid Maturation Pathway"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Acidianus Tailed Spindle Virus: A New Structural Paradigm for Viral Assembly"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"Capsid Forming Lumazine Synthase as a Container for Enzymatic Reactions"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:25 pm
"Decoration Mechanism of PhageL Capsids"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
"Interplay of Protein and Membrane Intermediates During Influenza Virus Fusion"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
"Molecular Simulations to Characterise Viral Membranes and Their Interactions"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Single-Particle Studies of Chikungunya Membrane Fusion"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Role of RNA in HIV Assembly"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"Design of Protein Origami Cages"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Pronanotechnology (Nanoparticle Prodrugs): In-Vivo Self-Assembly for Enhanced Biodistribution"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Designing Viruses as Biocomputing Nanodevices"
11:30 am - 11:40 am
Discussion
11:40 am - 12:05 pm
"How Icosahedral Shells Assemble on and Bud from Fluid Cargoes and Lipid Membranes"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Tobacco Mosaic Virus as a Nanocarrier for Drug Delivery"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Enabled Studies of Viruses
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:45 pm
"Design, Structure and Applications of Scalable Protein Cages"
6:45 pm - 7:00 pm
Discussion
7:00 pm - 7:35 pm
"Virion Dynamics and Immunogenicity Profile: Combining These Data to Develop an Efficient Vaccine Against Dengue and Zika Viruses"
7:35 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure