Conference Description
The Physiology, Biology and Pathology of Phosphate GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Phosphate is an essential mineral that is required for cell and organ function. Altered phosphate balance contributes to a variety of diseases. Maintaining phosphate balance involves complex interaction between several organs, and endocrine and metabolic regulators. The Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) on Physiology, Biology and Pathology of Phosphate focus on the latest advances in this field, integrating basic science and clinical relevance. The 2025 GRC is designed to attract a vibrant community of junior and established basic scientists, clinical researchers, and physicians, from across the world to facilitate opportunities for networking between diverse disciplines. We will discuss cutting-edge science and innovations on multiple exciting aspects of phosphate research. Among these, the conference program includes plenary sessions dedicated to the endocrine and local regulators of phosphate metabolism, the crosstalk between phosphate and iron metabolism, the importance of phosphate balance in skeletal health, and the impact of dietary phosphate on phosphate balance. We will discuss how these intersect in diseases associated with phosphate excess and deficiency, novel mechanisms of vascular and ectopic calcifications, and ongoing clinical trials and novel therapies that address phosphate disorders. Additionally, to gain a fresh perspective on the mechanisms of phosphate metabolism, we will learn from interesting studies performed in various different species. Finally, the program features a Power Hour session that addresses networking without borders, multiple poster sessions, and downtime for social activities and networking.
We welcome abstract submissions from all participants. Best ranking abstracts submitted prior to December 8th, 2024 will be integrated in plenary sessions as short oral presentations.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by October 12, 2024. Please check back for updates.
Keynote Session: Balancing Phosphate Metabolism
Discussion Leaders
-
Rosa Maria Affonso Moysés (Universidade de São Paulo, Brazil)
-
Tom Nickolas (Columbia University, United States)
Speakers
-
Christian Faul (University of Alabama at Birmingham, United States)
-
Kenneth White (Indiana University School of Medicine, United States)
PTH and Vitamin D Regulation
Discussion Leaders
-
Harald Jueppner (Massachusetts General Hospital, United States)
-
Michael Collins (National Institute of Dental and Craniofacial Research, NIH, United States)
Speakers
-
Michaela Fuchs (Duke University, United States)
-
Roberto Pacifici (Emory University, United States)
Interplay Between Iron, Phosphate, and FGF23
Discussion Leaders
-
Valentin David (Northwestern University, United States)
Speakers
-
Jane Joy Thomas (Northwestern University, United States)
-
Myles Wolf (Duke University, United States)
Hereditary and Acquired Bone Disorders
Discussion Leaders
-
Hanne Jørgensen (Department of Clinical Medicine, Nephrology; Aarhus University; Aarhus, Denmark)
Speakers
-
Marie-Hélène Lafage-Proust (Inserm u 1059 Sainbiose Universite Jean Monnet Saint-Etienne France, France)
-
Outi Makitie (University of Helsinki, Finland)
-
Petra Simic (Massachusetts General Hospital, United States)
Extra-Osseous Calcifications
Discussion Leaders
-
Marc Vervloet (Radboud University Medical Center, The Netherlands)
Speakers
-
Edward Smith (The Royal Melbourne Hospital & University of Melbourne, Australia)
-
Jakob Voelkl (Johannes Kepler University Linz, Austria)
-
Catherine Shanahan (King's College London, United Kingdom)
Phosphate Transport
Discussion Leaders
-
Hiroko Segawa (Tokushima University, Japan)
Speakers
-
Adolfo Saiardi (University College London, United Kingdom)
-
Clemens Bergwitz (Yale School of Medicine, United States)
Dietary Phosphate
Discussion Leaders
-
Kathleen Hill Gallant (University of Minnesota, United States)
Speakers
-
Isabel Rubio-Aliaga (University of Zurich, Switzerland, Switzerland)
-
Sharon Moe (Indiana University School of Medicine, United States)
-
Wanpen Vongpatanasin (University of Texas Southwestern Medical Center, United States)
Evolutive Mechanisms of Phosphate Balance
Discussion Leaders
-
Orson Moe (UT Southwestern Medical Center, United States)
-
Mathias Haarhaus (Karolinska Institutet, Sweden)
Speakers
-
Norbert Perrimon (Harvard Medical School, United States)
-
Seth Donahue (UMass Amherst, United States)
-
Marc Prentki (Université de Montréal, Canada)
Translation to Interventions in Humans
Discussion Leaders
-
Tamara Isakova (Northwestern University, United States)
-
Agnès Linglart (Paris Saclay University, France)
Speakers
-
Cassianne Robinson-Cohen (Vanderbilt University Medical Center, United States)
-
Isidro Salusky (David Geffen School of Medicine at UCLA, United States)
The GRC Power Hour™
Organizers
-
Rosa Maria Affonso Moysés (Universidade de São Paulo, Brazil)
-
Tom Nickolas (Columbia University, United States)