Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Plant Metabolic Engineering for Advancing Human Health and Sustainability
7:40 pm - 8:25 pm
"Integrating Network Science and AI: Insights from the Foodome Project"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
"Recombinant Production of Plant Secondary Metabolites and Enzymes for Biotechnological Applications"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Integration of Artificial Intelligence
9:00 am - 9:30 am
"Structure-enabled Enzyme Function Prediction Unveils Elusive Terpenoid Biosynthesis in Archaea"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Boosting Mass Spectrometry-based Metabolomics with Machine-Learning Powered Analogue Search, Substructure Discovery, and Cross-Ion Mode Matching."
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Controllable Protein Design and Engineering with Reinforcement Learning"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Generative Foundation Models Enable Bio-retrosynthesis of Natural Products"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Discovery of Iridoid Cyclase Completes Iridoid Pathway in Asterids"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Innovations in Plant Enzyme Engineering
6:00 pm - 6:30 pm
"Unusual Enzyme Reactions in Natural Product Biosynthesis"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Remodeling and Molecular Editing of Plant-derived Natural Products with Engineered Metalloenzymes"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Breaking Boundaries: Engineering Plants to Produce Nutrients They Never Evolved to Make"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Harnessing the Therapeutic Potential of Medicinal Plants through Discovery and Bioengineering
9:00 am - 9:30 am
"Ethnobotany as a Tool for Natural Product Drug Discovery"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Novel Chemistry and Enzyme Classes in Medicinal Plants"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Turning Bitter Lupins Sweet - Biosynthesis and Transport of the Lupin Alkaloids"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Specialized Cells for Plant Specialized Metabolism? The Example of Hyperforin and Hyper Cells in St. John’s Wort"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Discovery of Widespread Plant Defense Compounds Against Cross-kingdom Pathogens"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Consideration of Plant-Microbe Interactions for Plant Metabolic Engineering
6:00 pm - 6:30 pm
"High-throughput Approaches for Engineering the Plant Rhizosphere Microbiome"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Endophytes as Drivers of Bioactive Compound Production in Plants"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Interactions at the Root-Soil Interface: How Commensal Rhizobacteria Influence Plant Immunity and Metabolism"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Plant-Based Foods and Their Relationship to Human Health and Diseases
9:00 am - 9:30 am
"Biology and Chemistry of Plant Molecules in the Diet"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Engineering Tolerance Using Our Understanding of How Human Antibodies Recognize Allergens From Plants"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Pathway and Transport Engineering for Sustainable Production of Plant-Based Protein Food"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"The Periodic Table of Food Initiative: A Comprehensive Standardized Platform for Cataloging the Diversity of Plant Chemistry"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Engineering Plants for Enhanced Nutrition
6:00 pm - 6:30 pm
"Toward Tailored Seeds Amino Acid Biofortification"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"New Strategies for Engineering Nutrient-enriched Cucurbitaceae Crops"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Apocarotenoid Metabolism Involves Unexpected Cytochrome P450 Reactions"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Plant Engineering for Climate Resilience
9:00 am - 9:30 am
"Synthetic Genetic Circuits for Cell Type-specific Reprogramming of Gene Expression in Plants"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Engineering Rubisco Activase for Crop Thermotolerance"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Interplay Between Conjugated Sterol Metabolism and the Whole Cell Metabolic Status in Tomato"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Strategies to Improve Photosynthetic Carbon Metabolism to Enable Increased Crop Yield"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Plant Defense Through Protein Excretion and mRNA Delivery"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Industrial Applications of Plant Metabolic Engineering
6:00 pm - 6:20 pm
"Brassinosteroid-driven Metabolic Adaptation to Abiotic Stress"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Putting a New Spin on an Old Technology: Using Plant Cell Culture to Make Botanical Ingredients"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Improving Food System Sustainability using SEEDesignTM"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Scientific Publishing in a Time of Accelerated Discovery, Global Shifts, and AI"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure