Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
7:40 pm - 8:00 pm
"M6A-Mediated RNA Regulation at Single-Cell Resolution"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Cell Surface GlycoRNA Biology"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Role of RNA Substrate Specificity in Post-Transcriptional Gene Regulation"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Discriminating Self and Nonself dsRNA during Antiviral Defense"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
RNA Mechanisms in Disease
9:00 am - 9:20 am
"Novel Recognition of m6 A in an RNA Virus"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Warfare of Extracellular RNAs Between Plants and Fungal Pathogens"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"mRNA Stabilization By Chemical Modifications In Drug-Resistant Glioblastoma"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Post-Transcriptional Silencing Of Nuclear Poly(A) Binding Protein Is Critical For Cardiac Maturation And Function."
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Control of Epithelial Tissue Organization by mRNA Localization"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Mechanistic Insights of RNA Toxicity and Disrupted RNA Processing from Modeling Myotonic Dystrophy in Mice"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"TDP-43 Inhibits RNA Accumulation in Neurites"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"QKI Regulated Alternative Splicing Hints At A Novel Mechanism For Enhanced Exon Inclusion"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourโข
The GRC Power Hourโข is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Mechanisms and Consequences of RNA Duplex Formation during Transcription and Splicing"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Alternative Splicing in Muscle Cell Biology and Physiology"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Structural Studies of Intron Recognition by The Human Spliceosome"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Regulation of Innate Immune Signaling by Alternative Splicing"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Promoter-Proximal Transcriptional Termination in Mammals"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"A Nuclear RNA Degradation Code For Short, Capped, And Polyadenylated RNAs"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Investigating The Mechanisms Governing Alternative Promoter Usage"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Sequence Determinants of Bacterial mRNA Stability"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Transcriptional Control of Stress and Immune Responses"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"The communication from mRNA decay to the transcriptional machinery"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"An Ancient Poison Exon with Polyamine-Sensitive Alternative RNA Folding Promotes Homeostatic Control of Polyamine Levels in Vertebrates"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Structural Insights into RNA 3'-End Processing"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"The Unique RNA Signatures of The Nervous System: Regulation and Function"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"mRNA Initiation and Termination Are Spatially Coordinated"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Regulation of mRNA Translation and Decay"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Co-Transcriptional Assembly of RNA-Protein Complexes"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Elucidating Key Structure-Function Relationships of the METTL16โขMALAT1 Triple Helix Complex"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Investigating the Functional Roles of RNA Structure in Plants"
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"New Tools for Discovery and Characterization of Complex RNA and RNP Structures"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"DEAD-Box ATPases as Regulators of RNA-Containing Membraneless Organelles"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Probing RNA Folding with High-Throughput Approaches: New Tools and Insights into RNA Chemistry and Gene Regulation"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"A novel RNA thermosensor element regulating teichoic acid biosynthesis in obligate human pathogen Streptococcus pneumoniae "
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Regulation And Specificity Of dsRNA Binding"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
RNP Structure and Function
7:30 pm - 7:50 pm
"mRNP Configurations Before, Within and Beyond the Nuclear Pore Complex"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Protein Disorder and Direct RNA Binding"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Protein-RNA and Protein-Protein Interactomes to Study RNA Biology"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Riboregulatioin: Biology, Mechanisms and Scope"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Natural Therapeutic Noncoding RNA 4.5SH : Targeting and Skipping Toxic Exons"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"G3BP1 mRNA Hybrids at Focal Adhesion Proteins Regulate Cell Migration"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Decoding The RNA Structurome and Interactome in Living Cells"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Conserved Functions of Deeply Conserved MicroRNAs"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Transcriptome-Wide mRNA Condensation Excludes Stress Induced Transcripts"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Investigating Cis And Trans Regulatory Factors That Govern Long Noncoding RNA Splicing"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"New Functions for Noncoding RNAs in Mammals"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanisms of Translation
7:30 pm - 7:50 pm
"tRNA Splicing Defect Underlies Neural Crest Cell Pathologies"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"The Impact of Coding Regions on Gene Regulation"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Seeing Ribosome Assembly in Action"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Concentration Matters: Ribosome Function Beyond Protein Synthesis"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure