| SUNDAY |
| 2:00 pm - 8:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | General Introduction to Posttranslational Modifications |
| 7:40 pm - 7:50 pm | Discussion Leader: Ning LI (The Hong Kong University of Science and Technology) |
| 7:50 pm - 8:30 pm | Al Burlingame (University of California, San Francisco, USA)
"Progress in defining and deciphering the roles of O-GlcNAcylation and phosphorylation in protein biology" |
| 8:30 pm - 8:35 pm | Discussion |
| 8:35 pm - 9:15 pm | John Yates (The Scripps Research Institute, USA)
"The Landscape of Post-Translational Modifications in the Genetic Disease Cystic Fibrosis" |
| 9:15 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PTM Sites Identification and biological functions |
| Discussion Leader: Al Burlingame (University of California, San Francisco, USA) |
| 9:00 am - 9:30 am | Jian Kang Zhu (Shanghai Center for Plant Stress Biology, CAS, China and Purdue University, USA)
"Regulatory role of protein PTM in ABA and drought stress responses" |
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:15 am | Group Photo / Coffee Break |
| 10:15 am - 10:45 am | Ole N. Jensen (University of Southern Denmark)
"Mapping PTMs in cellular organelles by mass spectrometry" |
| 10:45 am - 10:50 am | Discussion |
| 10:50 am - 11:20 am | Henry Lam (The Hong Kong University of Science and Technology, Hong Kong SAR, China)
"Computational methods for high-throughput PTM identifications by shotgun proteomics" |
| 11:20 am - 11:25 am | Discussion |
| 11:25 am - 11:55 am | Pengyuan Yang (Fudan University, China)
"The new N-glycan quantitative techniques based on biological mass spectrometry" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:25 pm | Taishi Umezawa (Tokyo University of Agriculture and Technology, Japan)
"Phosphoproteomic approaches to understanding ABA signaling networks in plants" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Molecular and cellular proteomics |
| Discussion Leader: Zhiyong Wang (Carnegie Institution for Science, Stanford, USA) |
| 7:30 pm - 8:00 pm | Waltraud Schulze (University of Hohenheim)
"Analysis of time-resolved phosphorylation networks in Arabidopsis thaliana" |
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:35 pm | Paul Insel (University of California, San Diego)
"Cyclic AMP/protein kinase A-mediated regulation of cell function: proteomics and mitochondrial sub-proteomic analysis" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:10 pm | Ariel Bensimon (ETH Zurich)
"Systems-level PTM analysis by targeted proteomics" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Chor Teck Tan (AB SCIEX)
"Application of Differential Ion Mobility Spectrometry in Separation, Identification and Characterization of Post-Translational Modified Peptides" |
| 9:25 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Cellular phosphorylation |
| Discussion Leader: Michael Sussman (University of Wisconsin, Madison, USA) |
| 9:00 am - 9:30 am | Scott C. Peck (University of Missouri)
"Integrating phosphoproteomics, bioinformatics, and functional genomics to elucidate signaling networks during plant biotic stress responses" |
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:05 am | Jonathan Trinidad (Indiana University)
"Phosphorylation in the central nervous system: Interactions between phosphorylation and other post-translational modifications" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:25 am | Coffee Break |
| 10:25 am - 10:55 am | Hong-Wei Xue (Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, CAS)
"Phosphorylation modification in plant hormone effects" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:30 am | W.L. Wendy Hsiao (Hong Kong Baptist University)
"Investigation of the impacts of Gynostemma triterpenoids on cancer, inflammation, and gut microflora using systems biology approach" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:05 pm | Jay J. Thelen (University of Missouri)
"Plant phosphoproteomics - from discovering phosphorylation sites to identifying kinase clients" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Maarten Altelaar (Utrecht University)
"Ti4+-IMAC and EThcD dramatically improve enrichment and unambiguous phosphosite identification enabling efficient profiling of phosphoproteome dynamics" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Quantitative and functional phosphoproteomics |
| Discussion Leader: Chentao Lin (University of California, Los Angeles, USA) |
| 7:30 pm - 8:00 pm | Michael Sussman (University of Wisconsin-Madison)
"Isotope-assisted mass spectrometric measurements of phosphoprotein changes associated with plasma membrane-mediated signaling in Arabidopsis thaliana" |
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:35 pm | Rong Zeng (Shanghai Institutes for Biological Sciences, CAS)
"Global Phosphoswitch of Transcription Factors Initiating Cell-Fate Determination" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:10 pm | Frank L.H. Menke (Utrecht University)
"Antagonistic regulation of immune response and development by MAP kinase network signaling" |
| 9:10 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Sarah Zhang (University at Buffalo, SUNY, USA)
"Cellular signaling from the ER regulates endothelial inflammation and vascular function" |
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Kinase/phosphatase-mediated cell signaling networks |
| Discussion Leader: Lan Huang (University of California, Irvine) |
| 9:00 am - 9:30 am | Heribert Hirt (URGV Plant Genomics)
"Towards protein complex-based systems biology of MAPK signal transduction in plants" |
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:05 am | Sheng Luan (University of California, Berkeley)
"Ion channel regulation by interacting protein kinase-phosphatase pairs" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:25 am | Coffee Break |
| 10:25 am - 10:55 am | Martha Cyert (Stanford University)
"Global identification of Calcineurin Substrates Using Quantitative Phosphoproteomics" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:30 am | Jian-Min Zhou (Institute of Genetics and Developmental Biology, CAS)
"Activation of a plant immune receptor" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:05 pm | Zhi-Yong Wang (Carnegie Institution for Science)
"A complex signaling network integrating steroid, peptide, and pathogen signals in Arabidopsis" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Charles Liu (ASPEC, China)
"In-depth Phosphoproteome Analysis using PolyMAC" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Kinase/phosphatase and phosphoprotein interactomics |
| Discussion Leader: Pierre Thibault (Université de Montréal) |
| 7:30 pm - 8:00 pm | Chentao Lin (University of California, Los Angeles)
"CRY for help from LAPD -- a new tool for plant proteomics" |
| 8:00 pm - 8:05 pm | Discussion |
| 8:05 pm - 8:35 pm | Marcus Smolka (Cornell University)
"The DNA damage signaling network" |
| 8:35 pm - 8:40 pm | Discussion |
| 8:40 pm - 9:10 pm | Yasushi Ishihama (Kyoto University)
"Illuminating cellular phosphorylation network through quantitative phosphoproteomics for molecular-targeting drug discovery" |
| 9:10 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Mass spectrometry-based interactomics |
| Discussion Leader: Ole N. Jensen (University of Southern Denmark) |
| 9:00 am - 9:30 am | Steven Briggs (University of California, San Diego)
"Reconstruction of Protein Networks from an Atlas of Maize Proteotypes" |
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:05 am | Pierre Thibault (Université de Montréal)
"Large-scale quantitative proteomics analyses of protein SUMOylation in human cells" |
| 10:05 am - 10:10 am | Discussion |
| 10:10 am - 10:25 am | Coffee Break |
| 10:25 am - 10:55 am | Don Kirkpatrick (Genentech, Inc.)
"Interrogation of site specific ubiquitination reveals substrates for E3 ligase and DUB enzymes" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:30 am | Lan Huang (University of California, Irvine)
"Deciphering interactome dynamics of protein complexes using integrated proteomic approaches" |
| 11:30 am - 11:35 am | Discussion |
| 11:35 am - 12:05 pm | Jesper Velgaard Olsen (University of Copenhagen)
"Global analysis of cell signaling networks by quantitative phosphoproteomics" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Mary Waye (The Chinese University of Hong Kong, China)
"Studies on Sumoylation of Zinc Finger Protein ZNF146" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | PTM networks and molecular systems biology |
| Discussion Leader: Heribert Hirt (URGV Plant Genomics) |
| 4:00 pm - 4:30 pm | Angela Tyner (University of Illinois, College of Medicine, USA)
"Activation of Protein Tyrosine Kinase 6 at the Plasma Membrane Promotes the Epithelial Mesenchymal Transition in Prostate Cancer" |
| 4:30 pm - 4:35 pm | Discussion |
| 4:35 pm - 5:20 pm | Tony Hunter (The Salk Institute for Biological Studies)
"Crosstalk between post-translational modifications" |
| 5:20 pm - 5:30 pm | Discussion |
| 6:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
