Sunday
2:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Cellular Signaling Networks and Controls
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:25 pm
"Quantitative Peptidoform Profiling by SWATH/DIA Mass Spectrometry"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"Building Protein Signatures of Cardiovascular Diseases from Unstructured Data: A Machine Learning-Based Text Mining Approach"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"Reconstructing Dynamic Regulatory and Signalling Response Networks"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Kinases, Gene Regulation and Chromatin Dynamics
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Molecular Analysis of Histone Modification Readout"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Chromatin Phosphoproteomics to Understand Biotic Stress Signaling in Arabidopsis "
10:05 am - 10:10 am
Discussion
10:10 am - 10:40 am
"Systematic Interaction Profiling of Human Bromodomain-Containing Proteins Reveals Complex Modes of Binder Recruitment for BET Proteins"
10:40 am - 10:45 am
Discussion
10:45 am - 11:25 am
Group Photo / Coffee Break
11:25 am - 11:40 am
"Dynamics of Histone Acylations During Mammalian Spermatogenesis"
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Activation Mechanisms of the Hippo Kinase Cascade"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:20 pm
"The Landscape of Histone Modifications in a High-Fat-Diet-Induced Obese (DIO) Mouse Model"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Roles and Functions of Protein Glycosylation
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Protein O-GlcNAcylation: The Occurrence, Sites and Biological Functions Revealed by ETD MS"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Functional Analysis of Glycosylation by Identification of Proteins and Pathways Associated with Glycogene Expression"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Effective Chemical and Enzymatic Methods to Globally Characterize Protein Glycosylation"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"PTM-Invariant Peptide Identification Using Coding Method "
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Miscellaneous PTMs and Biological Functions
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Oxidative Post-Translational Modifications of Cysteine Residues in Plant Signal Transduction"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Regulation of the 26S Proteasome by Reversible Phosphorylation"
10:05 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Machine Learning Approaches for Enhancement of Actionable Knowledge Accumulated Through MS-Based PTM Detection"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Adapting Functional Protein Microarrays to Include Post Translational Modification. New Territory for Identifying Biomarkers and Therapeutic Targets"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Evading RIG-I-Mediated Innate Immune Response by Protein Deamidation"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Revealing Nascent Proteomics In Vivo in Signaling Pathways and Cell Differentiation"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"The Synthesis of Proteins with Site-Specific Lysine Methylation/Acylation Using an Expanded Genetic Code"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
2:00 pm - 4:00 pm
Poster Session
4:00 pm - 6:00 pm
Roles and Functions of Protein Phosphorylation
4:00 pm - 4:10 pm
Introduction by Discussion Leader
4:10 pm - 4:35 pm
"Regulation of Receptor Kinase-Mediated Innate Immunity"
4:35 pm - 4:40 pm
Discussion
4:40 pm - 5:05 pm
"How Does a Plant Receptor Regulate Heterotrimeric G Proteins?"
5:05 pm - 5:10 pm
Discussion
5:10 pm - 5:25 pm
"The Role of SnRK2.4 and SnRK2.10 Kinases in Plant Response to Long Term Salt Stress"
5:25 pm - 5:30 pm
Discussion
5:30 pm - 5:45 pm
"Interplay of MAPK Signaling and Calcium-Regulated Transcription in Plant Innate Immunity"
5:45 pm - 5:50 pm
Discussion
5:50 pm - 6:00 pm
General Discussion
6:00 pm - 7:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Protein Ubiquitination and Protein Complexes
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Ubiquitin-Dependent Regulation of Cell Growth and Division"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Mass Spectrometry of Protein Complexes, Modifications, and Their Impact on Metabolism"
10:05 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Regulation of the Stress-Activated Degradation of Mitochondrial Respiratory Complexes in Yeast"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Aberrant Glycosylation Affects Protein Function Having Implications in Disease Diagnostic and Therapeutics"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
"Structural and Mechanistic Understanding of USP7 Activation Through the Discovery and Development of Small Molecule Inhibitors of USP7"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Estimating the Total Number of Phosphoproteins and Phosphorylation Sites in Eukaryotic Proteomes"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Redox Modifications and Its Regulation of Protein Function"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"Targeted Proteomic Approaches for Interrogating the Human Kinome"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Lysine Crotonylation: Enzymes and Functions"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Dissecting Cellular Signaling Networks by Quantitative Phosphoproteomics"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Large-Scale Identification of Cell-Specific PARP Substrates"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Role of PTMs in Novel Pathways
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Proteome Is an Epigenetic Phenomenon"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"A Sleigh Ride Through the SNO: Role of S-Nitrosylation in Plant Immunity"
10:05 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 10:55 am
"Remodeling of the Muscle Signaling Network with Age"
10:55 am - 11:00 am
Discussion
11:00 am - 11:15 am
"Apoptosis Signal Regulating Kinases-Linking Redox Stress to MAPK Signaling"
11:15 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Arginine Methylation Modulates BMP-Smad and Non-Smad Signaling"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Revealing Complex PTMs Schemes on Transcription Factors Using NMR Spectroscopy"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Mapping Proteome-Wide Targets of Protein Kinases in Response to Environmental Stresses"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
PTM Cross-Talk and Cellular Pathways
4:00 pm - 4:40 pm
"Isoaspartic Acid, Its Role and Network - A Proteomics Study"
4:40 pm - 4:50 pm
Discussion
4:50 pm - 5:30 pm
"Regulatory Elements and Functions of Short-Chain Lysine Acylations"
5:30 pm - 5:40 pm
Discussion
5:40 pm - 6:00 pm
General Discussion
6:00 pm - 7:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure