Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Leveraging Data for Patient Centric Drug Product Design and Development in Addressing Unmet Medical Needs
7:40 pm - 8:25 pm
"Pre-Clinical Form an Formulation Requirements for Low to Middle Income Countries"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 9:20 pm
"Biopharmaceutics: A Phoenix Rising out of the Ashes of Irrational Formulation Design"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Formulation and Manufacturing Technologies for the Future
9:00 am - 9:45 am
"Manufacturing Technologies for ALD Coating To Enable Single Shot Vaccines"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"Manufacture of High Concentration mAbs for SubQ Delivery"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Transbuccal Delivery of Peptides with the Suction Patch"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Patient Centric Formulation Design and Translation for Small Populations
7:30 pm - 8:00 pm
"Rational and Simulation-Based Design of RNA Nanocarriers for Inhalation Therapy"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Pediatric Product Development Platforms"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Point-of-Care Drug Delivery – 3D Printing Pills"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Replacement, Reduction and Refinement of Pre-Clinical Testing: In Silico and In Vitro Tools for Formulation Design
9:00 am - 9:45 am
"Advancing Formulation Science Using In Vitro Models of the Intestinal Mucosa"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"A Journey Towards Choosing the Right Formulation: The Significance of PBBM"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Utilizing PBPK/PBBM to Streamline Formulation Design and Development"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Artificial Intelligence and Other In Silico Methodologies to Guide Formulation Design
7:30 pm - 8:00 pm
"Computational Pharmaceutics - A New Paradigm of Drug Delivery"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Simple Biorelevant Bicarbonate Buffer System for Dissolution Testing: Floating Lid Method"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Machine Learning for Drug Development and Delivery"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Overcoming Biological Barriers in Drug Delivery
9:00 am - 9:45 am
"Oral Delivery of Macromolecules Considering the Mucus and Cell-Barrier"
9:45 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 11:15 am
"Overcoming Barriers to Lymphatic Delivery to Enhance Drug Exposure and Effect"
11:15 am - 11:30 am
Discussion
11:30 am - 12:15 pm
"Engineering Macromolecules and Delivery Systems for Navigating Biological Barriers"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Analytical Tools Utilizing Simulation and Modeling for Form Selection and Formulation Development
7:30 pm - 8:00 pm
"Pharmaceutical Structures and Their Changes Interrogated with Multimodal Nonlinear Optics"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Lilly In Vitro Model for Peptide Delivery"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Confronting Unpredictability in Solid Form Science: Leveraging Advanced Computational and Analytical Techniques to Address Molecular and Phase Complexity"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Lessons Learned in the Development and Translation of Complex Pharmaceutical Products
9:00 am - 9:35 am
"AI Applications in Subvisible Particle Characterization: From Process Monitoring to Exploratory Data Analysis"
9:35 am - 9:45 am
Discussion
9:45 am - 10:20 am
"Assessing the Impact of Physical Instability on In vivo Performance of a Commercial Amorphous Product"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:35 am
"The Story of Inhaled Insulin"
11:35 am - 11:45 am
Discussion
11:45 am - 12:20 pm
"Scale-Up & Translation of Novel Drug Products: From Bench to Bedside"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Early Career Investigator Presentations
7:30 pm - 7:50 pm
Short Talk Selected from Poster Abstracts
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
Short Talk Selected from Poster Abstracts
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
Short Talk Selected from Poster Abstracts
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure