Conference Description
The Protein Folding Dynamics GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.
Biological life depends on motion, spanning femtoseconds vibrations of atoms in enzyme transition states to deleterious protein aggregation that can span days or even weeks. Our current understanding of in vitro protein folding is due to decades of experimental and computational research that provided high-resolution characterization of protein structure, identification of folding principles, and development of folding algorithms. Outstanding challenges surround linking protein dynamics with their function in crowded cellular environments, interaction with chaperones and other players in the cellular ecosystem, evolution of protein sequences, and biomedical applications. In this conference, we will bring together leading experts in protein science who study protein dynamics in the context of these complicated topics. We will leverage the development of AI based methods and high-throughput experiments to scale up our understanding of these dynamic processes from single folding pathways to the collective dynamics of proteins critical to homeostasis.
The topics, speakers, and discussion leaders for the conference sessions are displayed below. The conference chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by September 6, 2025. Please check back for updates.
Keynote Session: Protein Folding On and Off the Ribosome
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Protein Folding Fast and Slow
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Structural and Functional Aspects of Protein Allostery
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Exploring Sequence Space
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Mechanistic Insights from High-Throughput Experiment
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Folding in Cellular Context
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Scaling Up from Molecules and Phenotypes to Evolutionary Dynamics
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AI-Based Dynamics: Machine Learning for Protein Folding and Dynamics
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Keynote Session: Protein Dynamics In Vivo, In Vitro, In Silico
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The GRC Power Hour™
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