Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Techniques in Folding Dynamics
3:45 pm - 3:55 pm
"Measuring Transition Paths of Fast Folding Proteins by Single-Molecule FRET and Zero-Mode Waveguides"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"Large Scale Investigation of Protein Stability and Dynamics Using High-Throughput Hydrogen-Deuterium Exchange Mass Spectrometry"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"msmFRET Enables Comparison of MD and smFRET Datasets to Understand Conformational Heterogeneity Within Individual smFRET Populations"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Protein Engineering and Design
7:30 pm - 7:40 pm
"Role of a Calcium Binding Site Across Glycoside Hydrolase(GH) 9 Family Endoglucanases"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"The Genetic Architecture of Hydrophobic Protein Cores"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Expanding Protein Engineering with Proteins that Fold and Function in Water-Immiscible Solvents"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"A Billion Years of Evolution Manifest in Nanosecond Protein Dynamics"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Insights into the Degradation and Structural Dynamics of the First Crystal Double Knotted Protein TrmD-Tm1570 from Calditerrivibrio Nitroreducens"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Probing the Rules of Protein Structure, Function and Recognition Through the De Novo Design of Functional Proteins"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"High-Throughput Discovery of Inhibitory Protein Fragments with AlphaFold"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Protein Interactions and Dynamics
9:00 am - 9:10 am
"How Does GroEL Recognize Targeted Proteins?"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Conformational Ensembles Determine Selectivity in Prthologous Transcription Factors"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Unveiling the Dynamics of Binding and Folding in Ribonuclease S Formation"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Small Molecule Allosteric Modulators of the AML-associated Src-Family Kinase, Hck"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Experiment and Simulations Reveal Residue Details for How Target Binding Tunes Calmodulin’s Calcium Binding Properties"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"dGAE(297-391) tau Fragment Promotes Formation of CTE-Like Full-Length tau Filaments"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Thermodynamic Stability Change Prediction and Topological Features of Protein Phosphorylation in Cancer"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Strategies for Navigating Academic Job Searches
1:30 pm - 2:15 pm
"Strategies for Navigating Academic Job Searches"
2:15 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes