| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:35 pm | Chair’s Opening Remarks / Introductory Comments by GRC Site Staff |
| 7:35 pm - 9:30 pm | SPECIAL TOPIC: IMPORT INTO ORGANELLES |
| 7:35 pm - 7:45 pm | Discussion Leader: Ken Cline (University of Florida) |
| 7:45 pm - 8:10 pm | Ralph Erdmann (University of Bochum)
"Protein import into Peroxisomes" |
| 8:10 pm - 8:20 pm | Dicussion |
| 8:20 pm - 8:45 pm | Enrico Schleiff (University of Munich)
"Chloroplasts" |
| 8:45 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:20 pm | Walter Neupert (University of Munich)
"Protein Import Into Mitochondria" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:30 pm | Wine tasting and get-together party |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 9:35 am | IMPORT INTO ORGANELLES (continued) |
| 9:00 am - 9:25 am | Dennis Voelker (University of Denver)
"Protein Assemblies and Lipid Motifs Regulate Non-Vesicular Phospholipid Traffic in Organelle Biogenesis" |
| 9:25 am - 9:35 am | Discussion |
| 9:35 am - 12:30 pm | HOW TO PASS THROUGH THE TRANSLOCON |
| 9:35 am - 9:45 am | Discussion Leader: Jim Whelan (University of Perth) |
| 9:45 am - 10:10 am | Danny Schnell (University of Massachusetts)
"The role of the Toc-Tic machinery in protein targeting to chloroplasts" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 11:00 am | Coffee Break / Group Photo |
| 11:00 am - 11:25 am | Toshiya Endo (Nagoya University)
"Functional network of mitochondrial translocator complexes" |
| 11:25 am - 11:35 am | Discussion |
| 11:35 am - 12:00 pm | Tassos Economou (University of Crete)
"Bacterial Sec translocase: from structure to mechanism" |
| 12:00 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:20 pm | Masato Nakai (Osaka University)
"Identification and characterization of a novel preprotein translocation intermediate at the inner envelope of chloroplast" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | THE INTERMEMBRANE SPACE |
| 5:30 pm - 5:40 pm | Discussion Leader: Nikolaus Pfanner (University of Freiburg) |
| 5:40 pm - 6:05 pm | Kai Hell (University of Munich)
"The disulfide relay system in the biogenesis of intermembrane space proteins" |
| 6:05 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Kostas Tokatlides (University of Crete)
"Oxidative protein import, fodling and assembly in the mitochondrial intermemrbane space" |
| 6:40 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:15 pm | Agnieszka Chacinska (University of Freiburg)
"A multi-step assembly pathway for proteins of the mitochondrial intermembrane space" |
| 7:15 pm - 7:25 pm | Discussion |
| 8:00 pm | Dinner |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | TRAFFICKING IN ATYPICAL SYSTEMS |
| 9:00 am - 9:10 am | Discussion Leader: Tony Pugsley (Institute Pasteur Paris) |
| 9:10 am - 9:35 am | Trevor Lithgow (University of Melbourne)
"Evolution of pathways for sending proteins into mitochondria" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Francoise Jacob-Dubuisson (Institute Pasteur, Lille)
"Protein secretion by two partner systems: the FHA/FhaC model" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 10:30 am | Chris Stathopoulos (California State Polytechnic University)
"Autotransporter secretion: lessons from the serine protease autotransporters of enteric pathogens" |
| 10:30 am - 10:35 am | Discussion |
| 10:35 am - 11:05 am | Coffee Break |
| 11:05 am - 11:30 am | Geoffrey McFadden (University of Melbourne)
"Protein trafficking to the relict plastid of malaria parasites" |
| 11:30 am - 11:40 am | Discussion |
| 11:40 am - 11:50 am | Nikhil A. Thomas (Dalhousie University, Canada)
"The complexities of chaperone-effector interactions associated with type III secretion" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Jacqueline Gulbis (Walter and Eliza Hall Institute, Melbourne)
"Mitochondrial chaperones: precursor transfer in the inter-membrane space" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Nathan N. Alder (Texas A&M University)
"Structural and functional aspects of Tim23p revealed by fluorescence spectroscopy" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | MOLECULAR BASIS OF DESEASE RELATED TO TRAFFICKING |
| 5:30 pm - 5:40 pm | Discussion Leader: J.L. Brodsky (University of Pittsburgh) |
| 5:40 pm - 6:05 pm | Steve Claypool (UCLA)
"Mislocalized Taffazin and Barth Syndrome" |
| 6:05 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Dan N. Hebert (University of Massachusetts) |
| 6:40 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:15 pm | Yukio Fujiki (Kyushu University) |
| 7:15 pm - 7:25 pm | Discussion |
| 8:00 pm | Dinner |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GETTING TO TRANSLOCONS |
| 9:00 am - 9:10 am | Discussion Leader: Ida van der Klei (University of Groningen) |
| 9:10 am - 9:35 am | Ken Cline (University of Florida)
"The Tat protein transport system of plant thylakoids" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Colin Robinson (University of Warwick)
"Protein targeting by the Tat pathway in bacteria and chloroplasts" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 10:30 am | Wouter SP Jong (University of Amsterdam)
"Secretion of the E. coli autotransporter haemoglobin protease" |
| 10:30 am - 10:35 am | Discussion |
| 10:35 am - 11:05 am | Coffee Break |
| 11:05 am - 11:30 am | Danja Schuenemann (University of Bochum)
"SRP-dependent protein transport to the thylakoid membrane of chloroplasts" |
| 11:30 am - 11:40 am | Discussion |
| 11:40 am - 11:50 am | Robyn L. Goforth (University of Arkansas)
"The role of a structural switch mechanism in membrane binding by the signal recognition particle receptor in post-translational targeting" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Siegfried M. Musser (The Texas A&M)
"Two electrical potential-dependent steps are required for transport by the escherichia coli tat machinery" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Ophry Pines (Hebrew University of Jerusalem, Israel)
"A novel version of translation-coupled-translocation of a protein into mitochondria" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | GETTING TO TRANSLOCONS |
| 5:30 pm - 5:40 pm | Discussion Leader: Richard Wagner (University of Osnabrück) |
| 5:40 pm - 6:05 pm | Alison Baker (University of Leeds)
"Novel approaches for the study of peroxisome biogenesis and function" |
| 6:05 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Shou-ou Shan (Cal Tech)
"The role of noncanonical GTPases in co-translational protein targeting" |
| 6:40 pm - 6:50 pm | Disussion |
| 6:50 pm - 7:00 pm | Alice Robson (University of Bristol)
"Characterisation of conformational changes required for the opening of the SecY complex" |
| 7:00 pm - 7:10 pm | Discussion |
| 7:10 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 8:00 pm | Dinner |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE EUKARYOTIC SEC-TRANSLOCON: DIFFERENT APPROACHES AND DIFFERENT VIEWS |
| 9:00 am - 9:10 am | Discussion Leader: Matthias Müller (University of Freiburg) |
| 9:10 am - 9:35 am | Arnold Driessen (University of Groningen)
"The bacterial Sec translocase, a remarkable and dynamic machine" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:10 am | Roland Beckmann (LMU Munich)
"Different eukaryotic Sec translocons, new structural insights" |
| 10:10 am - 10:20 am | Discussion |
| 10:20 am - 10:30 am | Karin B. Romisch (University of Cambridge)
"Characterization of the interaction between the proteasome and the Sec61 channel at the ER membrane" |
| 10:30 am - 10:35 am | Discussion |
| 10:35 am - 11:05 am | Coffee Break |
| 11:05 am - 11:30 am | Irmi Sinning (University of Heidelberg)
"The SRP system of protein transport: news from an old friend" |
| 11:30 am - 11:40 am | Discussion |
| 11:40 am - 12:05 pm | Art E. Johnson (Texas A&M)
"Nascent chain control of ribosome-translocon conformation under native conditions" |
| 12:05 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Alf Honigmann (University of Osnabrück)
"Oligomerisation of the Sec61p and SecYEG complex in liposomes" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:30 pm | Poster Session |
| 5:30 pm - 7:30 pm | INTEGRATION OF PROTEINS INTO MEMBRANES |
| 5:30 pm - 5:40 pm | Discussion Leader: Colin Robinson (University of Warwick) |
| 5:40 pm - 6:05 pm | Rosemary Stuart (Marquette University)
"Biogenesis of mitochondrial inner membrane proteins: the role of Oxa1" |
| 6:05 pm - 6:15 pm | Discussion |
| 6:15 pm - 6:40 pm | Ross Dalbey (Ohio State University)
"Bacterial YidC insertase- Substrate Specificity and Function" |
| 6:40 pm - 6:50 pm | Discussion |
| 6:50 pm - 7:00 pm | Tom Silhavy (Princeton University)
"Envelope stress and outer membrane biogenesis in Gram-negative bacteria" |
| 7:00 pm - 7:25 pm | Discussion |
| 7:25 pm - 7:30 pm | Meeting Summary and discussion of future directions |
| 8:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
