Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Targeting of Substrates to the Membrane Transport Machinery
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"Molecular Chaperones and Protein Folding in the Cell"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Mechanisms of Protein Targeting to Cellular Membranes"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Molecular Topology of the Transit Peptide During Chloroplast Protein Import"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Structure and Mechanisms of Protein Translocases
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"Structural Insights into Protein Translocation Mechanisms Using Cryo-Electron Microscopy"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"An Update on Tail-Anchored Targeting from a Structural Perspective"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
"Structure of the Core of the Type Three Secretion System Export Apparatus"
11:10 am - 11:20 am
Discussion
11:20 am - 11:40 am
"Identification of Oxa1 Homologs Operating in the Eukaryotic Endoplasmic Reticulum"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Evaluating the Functional Pore Size of Chloroplast TOC and TIC Protein Translocons: Import of Folded Proteins"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Disposition of E. coli SecA Bound to Lipid Vesicles"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Membrane Transport and the Interface of Protein Transport with Transport-Associated Machinery
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Protein Import into Chloroplasts and Its Regulation by the Ubiquitin-Proteasome System"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Mitochondrial Machineries for Protein Translocation and Assembly"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Functions of Ribosome-Bound Factors in the Yeast Saccharoymces cerevisiae "
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Dissecting the Function of Components Comprising the Plasmodium Translocon of Exported P"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Membrane Protein Insertion and Dynamics
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"From Chaperones to the Membrane with a BAM!"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Mitochondrial Protein Transport Along the Presequence Pathway"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
"Pore-Forming Activity of the Pseudomonas aeruginosa Type III Secretion System Translocon Alters the Host Epigenome"
11:10 am - 11:20 am
Discussion
11:20 am - 11:40 am
"Structural Studies of the Mitochondrial Sorting and Assembly Machinery Complex"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Protein Dimerization Can Fix a Labile Membrane Protein Topology"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"How the Charge Balance Rule Governs Membrane Protein Topology"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Origins and Diversity of Membrane Transport Machinery
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:00 pm
"Substrate Recognition by the BAM Complex"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Mitochondria Protein and Lipid Transport"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"The Role of TPR Domains of Plant Mitochondrial Oxa Proteins"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Dual Sec Translocases and Function of GET3-Related Factors Within Chloroplasts"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Assembly of Membrane Transport Complexes
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"Receptor-induced Toxin Delivery During Bacterial Contact-Dependent Growth Inhibition (CDI)"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"The Transport of Proteins by the Twin Arginine Protein Transport Pathway"
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Mechanisms of Tail-Anchored Protein Triage"
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Molecular Pathways of Mitochondrial Outer Membrane Protein Degradation"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Analysing the Assembled Tat Translocase"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Membrane Trafficking of the Accessory Sec Transport Substrate and Machinery"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Protein Transport in Health and Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:55 pm
"Protein Transport in the Curli or Bacterial Amyloid Assembly Pathway"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:25 pm
"Can We Learn New Tricks from an Old Dog? Glycosome Biogenesis in an Ancient Eukaryote"
8:25 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Aberrant Secretory Proteins in Human Diseases"
8:55 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Targeting and Insertion of Pxa1, the Yeast Homologue of ALDP, a Peroxisomal ABC Transporter Important for Human Health"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Response of Protein Transport to Stress
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"The Mitochondrial UPR and Mitochondrial Protein Import Efficiency"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
10:05 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:10 am
"Malaria Parasites Co-Opt Human Hsp70 for Protein Translocation"
11:10 am - 11:20 am
Discussion
11:20 am - 11:40 am
"The TAM: A Nanomachine Responsible for the Assembly of Complex Outer Membrane Proteins"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Analysis of the Function of Beta-Barrel Assembly Machinery in the Bacteria by New Method EMM Assembly Assay"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Single Molecule Studies of the Bacterial Translocase SecA"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Systems/High-Throughput Approaches to Understanding Protein Transport and Organelle Biogenesis
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:00 pm
"Two Distinct Anionic Lipid Dependent Steps During Posttranslational Translocation"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Small Molecule Modulators for Mitochondrial Protein Import"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:00 pm
"Stabilizing Forces Holding the Nuclear Pore Ring Assembly"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"A High-Throughput Secretion Assay Reveals a Chaperone-Independent Type III Secretion Pathway"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure