Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Radionuclides and Molecular Targeting
Session in memory of Sam Gambhir and Tom O'Dorisio
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:25 pm
"Radiomolecular Precision Oncology: The Coda to Theranostics"
8:25 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"From Reactors to Bedside: Securing the Medical Radioisotope Supply Chain"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Current Radiotherapeutics and Theranostics in Oncology
9:00 am - 9:20 am
"Targeting Ligands for Theranostics; mAbs, Peptides, Pre-Targeting, and the Emerging Future"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Harnessing the Tumor Microenvironment - FAP and Beyond"
9:45 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Treatment of Glioma with Radiolabelled Substance-P and PSMA"
10:15 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"CXCR4 Based Theranostics"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Targeted Alpha Particle Therapy (212Pb) in PRRT Naïve Patients - A Promising Future Is Here"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Targeted Alpha Particle Therapy (225Ac) in Stable or Refractory PRRT Setting"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"68Ga-NOTA-AE105 uPAR PET in Patients with Neuroendocrine Neoplasms: Implications for uPAR Targeted Therapy"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Dosimetry-Guided Therapy with Radionuclides
7:30 pm - 7:50 pm
"Integrated Artificial Intelligence and Systems Biology for Personalised Radioligand Therapy"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Making Dosimetry Mainstream for Radionuclide Therapy for Cancer in Australia"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Incorporation of Dosimetry into Clinical Practice"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Challenges and Opportunities in the Dosimetry of Alpha Emitter Therapy"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Development of Theranostic Radiopharmaceuticals
9:00 am - 9:20 am
"Immunohistochemistry to Confirm Protein Targets in Cancer Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Development of Peptide-Based Radiopharmaceuticals - Native Peptides and Discovery Approaches"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:50 am
"Radiolabeled Monoclonal Antibodies for Radiotheranostics"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
"Current Status of Clinical Trials on FAP Targeted Radiopharmaceuticals"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Innovation in Radionuclide Thera(g)nostics: The Road(s) Ahead"
12:00 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Comprehensive Approach to Brain: Targeting the Blood Brain Barrier and Beyond with Radiotheranostics
7:30 pm - 8:00 pm
"Overcoming the Barriers to Better Understand and Treat Brain Diseases Using PET"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"From Brain PET Imaging to Peptide Receptor Radionuclide Therapy"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Glioma Associated Immune Cells: Potential Targets for Novel Theranostics Molecules"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Optimizing Therapy for Cancer Using Theranostics
9:00 am - 9:20 am
"PET Imaging Advancements for Radionuclide Theranostics"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Emerging Imaging Technologies for Theranostics - Gamma Camera to CZT SPECT"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Modern Approach to the Development of Radiopharmaceutical Therapies"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Exploring the Potential of PARP Inhibition to Sensitize SSTR2-Positive Small Cell Lung Cancer to 177Lu-DOTA-TOC PRRT"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"The Combination of Radionuclide Therapy and Immunotherapy - Emerging Understanding"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:15 pm
"Patient Perspective on Sequencing Therapies"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Design of Theranostic Clinical Trials
5:30 pm - 5:50 pm
"From Clinical Trials to EMA/FDA approval"
5:50 pm - 6:00 pm
Discussion
6:00 pm - 6:20 pm
"Pragmatic Clinical Trials Design in Theranostics"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 7:00 pm
"Regulatory Considerations in the Development of Radioligand Therapy: US FDA Perspective"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:30 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Advances in Radionuclide Theranostics
9:00 am - 9:20 am
"Small Change, Big Impact: A Holistic View on Pharmacokinetics of Radiometallated Peptide Multimers"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Towards Precision Radioligand Therapy: Total Body PET in Treatment Planning"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Combination Radionuclide Therapy: Dose Limiting Organ Differences in MIBG and PRRT for Maximizing Tumor Dose With Dosimetry"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"New Instrumentation for Detection of Alpha-Particle Effects in Tumor and Normal Tissues"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"New Biomarkers for Kidney Injury in the Development of Radiopharmaceuticals"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Radiation Biology and Theranostics: Current Knowledge and Emerging Understanding
7:30 pm - 7:50 pm
"Revisiting the Radiobiology of Targeted Alpha Particle Therapy for Cancer"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Radiobiology and Theranostics - Principles, Understanding, and Research Needs"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Role of cGAS and Extracellular Vesicles in Adaptive Immunity Induced by Targeted Radionuclide Therapy"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
General Discussion
9:20 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure