Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Radio and Immuno-Biology in Cancer Management
Discussion Leader: Daniel Kwon (University of Ottawa, Canada)
3:45 pm - 4:15 pm
Mara De Martino (Weill Cornell Medicine, United States)
"Fatty Acid Metabolism Limits Anti-Tumor Immunity Against Irradiated Glioblastoma"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Radiobiologic and Immunomodulatory Effects of Ionizing Radiation
Discussion Leader: Madeleine Landry (Stanford University, United States)
7:30 pm - 7:50 pm
Isabel Everard (Monash University, Australia)
"Radiobiological Responses to 177Lutetium-PSMA-I&T Therapy in Preclinical Models of Prostate Cancer"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
Ambika Parmar (UPMC Children's Hospital of Pittsburgh, United States)
"Radio-Immunologic Effects of Myeloid Cell Targeted RPT for Gliomas Using Lu-177 or Ac-225"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Maya Takashima (University of Wisconsin Madison, United States)
"Tumor Uptake and immunomodulatory Effects of 177Lu-PNT6555 in Multiple Syngeneic Murine Tumor Models"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Sarah Potiron (CNRS, France)
"The Role of Irradiation Parameters in Immunomodulation Following pMBRT Treatment in a Glioblastoma-Bearing Model"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Cancer Theranostics: New Targets, Compounds and Dosimetry Considerations
Discussion Leader: Maya Takashima (University of Wisconsin Madison, United States)
9:00 am - 9:20 am
Daniel Kwon (University of Ottawa, Canada)
"Potent C-X-C Chemokine Receptor 4 Radiotracers for High-Contrast PET/SPECT Imaging and Radioligand Therapy"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
Abraham Moses (Leland Stanford Junior University, United States)
"Non-Invasive Monitoring of Ferroptosis-Based Glioma Therapies Using a Radiotracer Specific to System xc-"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
Madeleine Landry (Stanford University, United States)
"Discovery and Validation of B7H3-Targeting Peptides for Radionuclide Theranostics"
10:20 am - 10:30 am
Discussion
10:30 am - 10:40 am
Paul Klauser (Memorial Sloan Kettering Cancer Center, United States)
"Targeting FGFR3 Oncogenic Mutation for Theranostics"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Between Academia and Industry: Which Path to Follow?
Discussion Leader: Andreas Goutopoulos (Actithera, United States)
1:30 pm - 2:30 pm
Panel Discussion
Academia and Industry: Which Path to Follow?
Claire Vanpouille-Box (Weill Cornell Medicine, United States)
Thierry Stora (CERN, Switzerland)
Anastasia Nikolopoulou (Johnson & Johnson, United States)
Sean X. Yan (UTSouthwestern Medical Center, United States)
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes