Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Immunogenicity of RNA Nanoparticles
3:45 pm - 4:10 pm
"Immunomodulation in RNA Nanotechnology"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Understanding Immunogenic Properties of Nucleic Acid Nanoparticles"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Therapeutic and Diagnostic Applications of RNA Nanoparticles
7:30 pm - 7:40 pm
"Photo-Controlled Release of Paclitaxel and Model Drugs from RNA Pyramids"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"RNA-DNA Fibers and Polygons with Controlled Immunogenicity Can Activate RNAi and Transcriptional Regulation of NF-kB"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Arrowtail RNA for Ligand Display on Ginger Exosome-Like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Screening, Selection and Characterization of Aptamers Against Ovarian Cancer Biomarker CA125"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Bioresponsive Quantum Dot Lattices for Applications in Biosensing and Conditionally Activated RNA Interference"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Universal Synthetic Technique of Nucleic Acid-Based Nanodetectors and Carrier-Free siRNA Delivery System"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"PTex: A Rapid and Unbiased Method for Cell-Wide Purification of Crosslinked RNA-Protein Complexes in Human and Bacteria"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Rapid, Affordable, Ultra-Sensitive Food Pathogen Biosensor, with Emphasis on Industrial Applicability"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
9:00 am - 9:10 am
"Metal Nanoparticles Capped with Structured RNA: The Spherical Incarnation of TectoRNA"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Palladacyclic Conjugate Group Promotes Hybridization of Short Oligonucleotides"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Comprehensive and Consistent Identification, Annotation, Extraction and Classification of RNA Multi-Helix Junction (MHJ) for Use in Nanotechnology Applications"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Cryo-EM Structure of Type III-A CRISPR-Cas Csm Complex"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Effects of RNA Nanoparticle Size, Shape, Structure, Sequence and Surface Chemistry on Biodistribution, Immunogenicity and Endosome Escape"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"A DNA Origami Platform for RNA Tertiary Structure Elucidation"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"Walk on the Origami Side: From Switchable DNA Nanodevices to Light-up Bio-Orthogonal RNA Nanoribbon"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"Expanding the Design Space of DNA Origami with Functional and Orthogonal Custom Scaffolds"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
This panel consists of laboratory leaders, research center directors, and industry scientists.
1:30 pm - 2:30 pm
Panel Discussion
Career Advice from Leaders in the Field
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes