Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
New Insights into Salmonella Epidemiology, Drug Resistance and Vaccines
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:15 pm
"Multidrug Resistant in Salmonella Infections in Africa and Role of Vaccine in Prevention and Control"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Epidemiology of Invasive Non-Typhoidal Salmonella Infections in Malawi"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Preclinical Mouse Model Systems to Identify the Basis for Effective Typhoid Vaccines"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
"Determinants of the Susceptibility of Nontyphoidal and Enteric Fever Salmonella Serovars to Serum Antibodies and Complement"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Molecular Mechanisms of Host-Pathogen Interactions
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Xenogeneic Silencing and the Maintenance of Conjugative Plasmids like pSLT"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"SPI1-Induced Changes in Motility and Chemotaxis"
9:50 am - 9:55 am
Discussion
9:55 am - 10:05 am
"A Comparison of Flagellar and SPI1 Type 3 Secretion Systems"
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
"New Weapons in (Micro)Biological Conflicts: T6SS Effectors with Structure-Specific Nuclease Activity"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Cost-Benefit Tradeoffs in Flagellum Assembly"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Non-Canonical Reprogramming of Host Transcriptional Pathways by Salmonella Typhimurium"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Salmonella Manipulates a Host DUB to Orchestrate the Rab-Mediated SCV Maturation"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
General Discussion
12:05 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Session in Memory of Josep (Pepe) Casadesus and Stefania Spanó: Interactions Between Salmonella and Host Cells
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Multimodular Imaging to Decipher the Different Intracellular Niches of Entero-Invasive Bacteria"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Salmonella Effector SopD Promotes Plasma Membrane Scission by Inhibiting RAB10."
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
"Identifying Host Vulnerabilities to Infections Using Single-Cell Genomics"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:50 pm
"Salmonella Genetics and Interactions with Host Cells"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Salmonella Interactions in the Intestine
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Micronutrients at the Host-Microbe Interface"
9:35 am - 9:40 am
Discussion
9:40 am - 10:05 am
"New Insights on Mucosal Immunity During Salmonella Infection"
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Decoding the Assembly and Biogenesis of Bacterial Microcompartments in Salmonella "
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Salmonella at the Intestinal Epithelial Surface - Insights from Imaging in Enteroids and Colonoids"
11:20 am - 11:25 am
Discussion
11:25 am - 11:50 am
"Modulation of Salmonella Typhimurium Virulence by Commensal Intestinal Fungi"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"Dissecting the Impact of Enteric Viral-Bacterial Co-Infection on the Host Innate Immune Response and its Implications for Pathogenicity"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
"Commensal Iron Acquisition Promotes Salmonella Evasion of Nutritional Immunity"
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Innate Immunity During Bacterial Infection
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Human inflammasome Responses to Salmonella Typhimurium"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Interaction of Salmonella with the Neonatal Intestinal Epithelium"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
"Caspase-7 Helps Intestinal Epithelial Cells Complete Extrusion Bucket Lists"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:50 pm
"Nitrate-Mediated Luminal Expansion of Salmonella Typhimurium is Dependent on CHOP"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Gene Regulation and Bacterial Signaling Networks
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Cyclic di-GMP Signaling in Salmonella Typhimurium"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Gene Regulation of Tartrate Metabolism in Salmonella Typhimurium"
9:50 am - 9:55 am
Discussion
9:55 am - 10:05 am
"Regulation of the Sulfite Stress Response in Salmonella "
10:05 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Control of Salmonella Virulence by Diffusible Signal Factors of the Intestine"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Steering Salmonella Within-Host Evolution"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Persistent Salmonella Infections in Humans are Associated with Mutations in the BarA/SirA Regulatory Pathway"
11:35 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Antibiotic-Tolerant Reservoirs of Salmonella are Determined by Bacterial Secretion Machinery"
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
"The Salmonella Typhimurium Effector SifA Controls Bacterial Dormancy in Epithelial Cells"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:15 pm
General Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Novel Approaches to Antimicrobial Resistance
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Rethinking Antimicrobial Discovery"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 7:05 pm
"Drug Screening Under Infection-Relevant Conditions Reveals Chemical Sensitivity in Multi-Drug Resistant Non-Typhoidal Salmonella (iNTS)"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
"Salmonella Typhimurium, Multidrug Resistance, and Cancer"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:50 pm
"Dual Regulatory Mechanism to Cope with Copper and Oxidative Stress in Salmonella Enterica "
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Evolution and Genomics of Salmonella- Host Interactions
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"The Role of Host Genetics in Salmonella Pathogenesis"
9:30 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Interplay Between Transcription and H-NS Silencing: Source of Phenotypic Heterogeneity in Genetically Identical Salmonellae "
9:55 am - 10:05 am
Discussion
10:05 am - 10:30 am
"Evolution of Human-Adapted Salmonella enterica from an Archaeogenetic Perspective"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:15 am
"Metabolism of Carbon Sources as Key Clade-Specific Determinants of Salmonella Enteritidis Associated with iNTS Disease"
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
"Unveiling the Small Protein Load of Salmonella "
11:30 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"New Actors Control the Shape of Intraphagosomal Salmonella "
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Finding the Weak Link: High-Throughput Fitness Experiments Reveal Specific Vulnerabilities of Human-Adapted Salmonella Isolates During Stress and Infection"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Emerging Technologies and New Challenges
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:35 pm
"Systems-Based Approaches to Dissect Salmonella 's Functions and Physiology"
6:35 pm - 6:40 pm
Discussion
6:40 pm - 6:50 pm
"A New Lipidomic Tool Identifies Previously Unknown Virulence Associated Salmonella Lipids"
6:50 pm - 6:55 pm
Discussion
6:55 pm - 7:05 pm
"Cytotoxic CD4+ T Cells and IFN-gamma Orchestrate the Induction of Apoptosis During Salmonella Typhimurium Infection"
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
"Characterizing Host-Pathogen Encounters at Early Stages of Infection"
7:35 pm - 7:40 pm
Discussion
7:40 pm - 7:50 pm
General Discussion
7:50 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure