SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | At the site of integrin adhesions |
3:45 pm - 4:15 pm | Cheng-Han Yu (National University of Singapore)
"Integrin activation triggers contractile movement and subsequent outward translocation of integrin-RGD clusters on supported membranes"
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4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I (Last names A-M) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Adhesion receptor signaling in cell migration |
| Discussion Leaders: Martin Schwartz (Yale School of Medicine) and Rosa Ng (Harvard Medical School) |
7:30 pm - 7:50 pm | Florian Sulzmaier (University of Hawaii Cancer Center)
"PEA-15 regulates glioblastoma cell migration through RSK2"
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7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Leolene Jean (Vanderbilt University)
"Activation of Rac by Asef2 promotes myosin II-dependent contractility to inhibit cell migration on type I collagen"
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8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Minggang Zhang (NIAID/NIH)
"Beta2 integrin LFA-1 triggers lytic granule polarization at natural killer cell synapses through ILK, gamma-parvin, and RhoGEF7"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Guillaume Jacquemet (University of Manchester)
"Filamin-A and IQGAP1 constrain Rac1 activity at sites of integrin activation via recruitment of RacGAP1"
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9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | New approaches to cell adhesion complexes and signaling |
| Discussion Leaders: Martin Humphries (University of Manchester) and Kimberly Stroka (Johns Hopkins University) |
9:00 am - 9:20 am | Adam Byron (University of Manchester)
"Proteomic analysis of integrin adhesion complexes reveals diverse cellular roles for adhesion signaling"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Benjamin Bangasser (University of Minnesota)
"Optimality in a motor-clutch cell traction model"
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9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Michael Bachmann (Karlsruhe Institute of Technology)
"Development and maturation of nascent adhesions visualized with superresolution microscopy"
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10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Cuc Bach (Children's Hospital at Westmead, Australia)
"The actin-associating protein Tm5NM1 inhibits protein trafficking to focal adhesions"
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10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II (Last names N-Z) |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Mentorship component: Navigating early career transitions |
| Discussion Leader: Valerie Weaver (University of California, San Francisco) |
1:30 pm - 2:15 pm | Valerie Weaver (University of California, San Francisco)
"Forcing transformation"
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2:15 pm - 2:45 pm | Discussion |
2:45 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |