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Stem Cells and Cancer (GRS)

Gordon Research Seminar

Emerging Technologies in Multi-Cellular Living Systems

May 13 - 14, 2023

Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Conference Description

The Stem Cells and Cancer GRS provides a unique forum for young doctoral and post-doctoral researchers to present their work, discuss new methods, cutting edge ideas, and pre-published data, as well as to build collaborative relationships with their peers. Experienced mentors and trainee moderators will facilitate active participation in scientific discussion to allow all attendees to be engaged participants rather than spectators.

In this meeting, scientists with various experiences will share their cutting edge research based technologies that promote tissue functions in multicellular living systems for regenerative potential, and how these approaches would impact organ repair and cancer progression to generate improved therapies. At the end of the meeting, there will be a Science Career panel featuring speakers from academia, government, and industry sharing their experiences for exploring/navigating diverse career paths for graduate students and postdocs.

Related Meeting

This GRS will be held in conjunction with the "Stem Cells and Cancer" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:00 pm - 3:15 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:15 pm - 4:00 pm	Self-Renewal and Differentiation: Lessons From Being a Postdoc to a Professor Discussion Leaders: and
3:15 pm - 3:45 pm	"Self-Renewal and Differentiation: Lessons from being a Postdoc to a Professor"
3:45 pm - 4:00 pm	Discussion
4:00 pm - 5:30 pm	Poster Session
5:30 pm - 7:30 pm	Stem Cells and their Niches Discussion Leaders: and
5:30 pm - 5:40 pm	"In Vivo Single-Cell Ribosome Profiling to Investigate Translational Regulation in Ageing Epidermal Stem Cells"
5:40 pm - 5:45 pm	Discussion
5:45 pm - 5:55 pm	"In Vivo Visualization of Stem Cell Dynamics in the Intestine During Homeostasis, Regeneration and Cancer"
5:55 pm - 6:00 pm	Discussion
6:00 pm - 6:10 pm	"The Transmembrane Proteoglycan Syndecan is Essential for Intestinal Stem Cell Maintenance and Division"
6:10 pm - 6:15 pm	Discussion
6:15 pm - 6:25 pm	"Advanced hiPSC-based 3D Settings to Unravel Fibrotic Programmes in Heart Pathologies"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:40 pm	"AQP5+ Pyloric Stem Cells Initiate Cancer and Mark a Putative Cancer Stem Cell Pool"
6:40 pm - 6:45 pm	Discussion
6:45 pm - 6:55 pm	"Loss of Kmt2d and Kmt2c Histone Methyltransferases Promotes Tumorigenesis and Displays a Gene Dosage Effect on EMT"
6:55 pm - 7:00 pm	Discussion
7:00 pm - 7:10 pm	"Defining the Role of the Revival Stem Cell during Growth and Therapy Resistance in Colorectal Cancer"
7:10 pm - 7:15 pm	Discussion
7:15 pm - 7:25 pm	"Crosstalk Between Tumour Vasculature and Ovarian Cancer Stem Cells: The Role of L1CAM"
7:25 pm - 7:30 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Cancer Cells, Microenvironment and Therapeutical Approaches Discussion Leader:
9:00 am - 9:10 am	"Injury Induces Wild-Type Cell Proliferation to Suppress Oncogenic Ras Cells"
9:10 am - 9:15 am	Discussion
9:15 am - 9:25 am	"In Vivo CRISPR Screen to Study Pre-Malignancy in Breast Epithelium at Single-Cell Resolution"
9:25 am - 9:30 am	Discussion
9:30 am - 9:40 am	"Multiple Mutant Clones Contribute to Epithelial Tumour Initiation"
9:40 am - 9:45 am	Discussion
9:45 am - 9:55 am	"Pharmacological Targeting Netrin-1 Inhibits EMT in Cancer"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	"Elucidating the Link Between Psoriasis and Skin Cancer"
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	"Dissecting the Cellular and Molecular Interaction Networks that Promote Melanoma Stemness at the Perivascular Niche"
10:25 am - 10:30 am	Discussion
10:30 am - 10:40 am	"Spatial Transcriptomics Reveals Multiple Melanoma Resistant Types in Patients"
10:40 am - 10:45 am	Discussion
10:45 am - 10:55 am	"The Lung Metastatic Niche: A Mirror of Cancer Cell Stemness"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Synthetic Biology: Programming Fate and Organization Discussion Leader:
1:30 pm - 2:10 pm	"Regeneration and Development, Two Faces of Forming Body Structures"
2:10 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under Award Number R13CA281327. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Conference History Stem Cells and Cancer

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