Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Nonequilibrium Statistical Mechanics
7:40 pm - 8:05 pm
"Putting the Laws of Nonequilibrium Statistical Physics on a Foundation as Solid as That of the Laws of Equilibrium"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Transport and Energetics of Bacterial Rectification"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Information Arbitrage in Molecular Machines"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Epistatic Hotspots Organize Antibody Fitness Landscape and Boost Evolvability"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Identification of Loci with Sustained Expression Fluctuations in Murine Embryonic Stem Cells"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"RNA World Fitness Landscapes and Evolution"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Synteny and Linkage Decay in Bacteriophage Pangenomes"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Statistical Structure of Genotype-Phenotype Maps: Null Expectations, Empirical Data and Implications for Evolution"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Towards a Single Cell Epigenetic Oscillator"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Noise is the Signal: Luria-Delbruck in High Resolution"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Emerge of Cell Fates in the Antibiotics Resistance Genes: The Role of Global Resource Allocation"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"How Selection Interacts with Population Density in a Finite Population"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Finding Signatures of Low-Dimensional Geometric Landscapes in High-Dimensional Cell Fate Transitions"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Nutrient Availability Shapes the Diversity and Stability of Microbial Communities"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Ecological Stability Emerges at the Level of Strains in the Human Gut Microbiome"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Combination Antibiotic and Phage Therapy of Bacterial Infections: What Models and Experiments Tell Us"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Effect of Ecological Interactions on the Distribution of Fitness Effects in Microbial Communities"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Emergence of Collective Coevolution in Microbial Ecosystems from Eco-Evolutionary Feedback"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Quantitative Physiology and Metabolism
9:00 am - 9:20 am
"Toward the Prediction and Control of Microbial Evolution: Analysis of High-Throughput Experimental Evolution"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Trainable Computation in Many-to-Many Molecular Networks"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Stochastic Aspects of Transcription"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Stochastic Dynamics of Early Tumor Growth"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Output Not Input: Nutrients, Growth Rate and Bacterial Cell Size"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Ultrasensitive Tuning of Cytoplasmic Viscosity via Active Noise"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Self-Regulation of Metabolism via Cofactor Dynamics"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Signatures of Energy Dissipation in Bacterial Chemotaxis Signaling Pathways"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Information Processing and Networks
7:30 pm - 7:50 pm
"Quantifying Mutual Information in the MAPK Signaling Pathway"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Phase Separation to Overcome Host Context Challenges in Synthetic Gene Circuit Design"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Structure and Mixing in Dynamic Mitochondrial Networks"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Localization and Diffusion of Proteins Sensitive to Membrane Lipid Packing"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Intermediate Time Scales Dynamics Explain Diversity of Presentations of Type 2 Diabetes"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Cell Fate and Development
9:00 am - 9:20 am
"Cell States Dictate Fidelity of Cellular Signaling"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Limits on Cellular Size Precision"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Designing the Timing and Time of Macromolecular Assembly Processes"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Intrinsic Versus Extrinsic Cellular Decision Making"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Higher Accuracy Through Higher Speed in Non-Equilibrium Systems"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Population Dynamics and Universal Statistics of Tumor-Inhabiting Bacteria"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Environment-Dependent Temporal Tuning of Phenotypic Heterogeneity in Salmonella Virulence Expression"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Dynamic Landscapes and Statistical Limits on Growth During Cell Fate Specification"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Mechanically-Driven Growth and Competition in a Voronoi Model of Tissues"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Machine Learning and Causal Inference
7:30 pm - 7:50 pm
"Dynamical Modelling of Genome Rearrangement Processes in Cancer Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Revealing Complex Single-Molecule Dynamics Using Bayesian Nonparametric FRET Analysis"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"A Differentiable Gillespie Algorithm for Simulating Chemical Kinetics"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Statistical Moments to Improve Parameter Inference from Microbial Data"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Detecting Significant Correlations Between Time Series"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Microbial Growth and Patterning
9:00 am - 9:20 am
"Harnessing the Wisdom of the Crowd: Watching Bacteria Coordinate Their Behavior in Groups"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Mathematical Modelling and Experimental Modulation of mRNA Localization in Brewer's Yeast"
9:40 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Antagonistic Interactions in Boom-and-Bust Environments: When Killers Don’t Always Win"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Localized Activation of Engineered Immune Cells for Tumor Therapy"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Glimpses of Gut Microbes in Actual Guts"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Deterministic Versus Stochastic Outcomes in Community Assembly Within the Structured Cyanosphere"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"A Non-Genetic Mechanism Creating Lineage-Associated Molecular Similarity from Stochastic Biochemical Reactions"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Noise-Driven Odd Elastic Waves in Living Chiral Active Matter"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Robust Germ Cell Fate Specification Driven by Embryonic RNA Condensates"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Novel Type of Self-Avoiding Walk Revealed by Influenza A's Motion on Coverslips: Optimal Kinetics and Mechanisms Driving Viral Locomotion"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Transcription and DNA Supercoiling"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Shaping Cellular Noise through Multicomponent Phase Separation"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Spontaneous Switching in a Protein Signaling Array Reveals Near-Critical Cooperativity"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure