Accelerating Understanding to Create the Next Generation of Synthetic Lethal Medicines After PARP Inhibitors

Join us for the inaugural GRC meeting on synthetic lethality in oncology. Synthetic lethality is a rapidly evolving field with importance for the development of oncology medicines. This meeting seeks to bridge the experimental and computational approaches that are leading to rapid advances and opportunities for translating synthetic lethality in the clinic.

Topics covered at the GRC will include:

- Lessons from the first wave of synthetic lethal targets in oncology;

- New experimental model systems and emerging molecular biology techniques for detecting synthetic lethality;

- Non-cell autonomous synthetic lethality;

- Measuring complex phenotypes in synthetic lethality;

- AI/ML and active learning methods in synthetic lethality;

- Biological pathways and complex systems as biomarkers;

- New synthetic lethal targets for drug discovery;

- Linking synthetic lethality functional genomics to clinical benefit.

Come join us for this exciting new GRC conference series.