Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Peptide Building Blocks
Discussion Leader: Rienk Eelkema (Delft University of Technology, The Netherlands)
7:40 pm - 8:00 pm
Introduction by Discussion Leader
8:00 pm - 8:35 pm
Sijbren Otto (University of Groningen, The Netherlands)
"Mechanisms of Emergence en Route to de-Novo Life"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:20 pm
Rein Ulijn (CUNY Advanced Science Research Center, United States)
"Peptide-Based Supramolecular Systems Chemistry"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Building Chemical Reaction Networks
Discussion Leader: Charalampos Pappas (University of Freiburg, Germany)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Max von Delius (Ulm University, Germany)
"Driving Organophosphates Out of Equilibrium"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
Sergey Semenov (Weizmann Institute of Science, Israel)
"Oscillators, Waves, and Patterns by Molecular Design"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
Ivan Aprahamian (Dartmouth College, United States)
"Coupled Negative Feedback Loops"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
Connor Coley (Massachusetts Institute of Technology, United States)
"Constructing and Learning from Networks of Organic Reactions"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Lorenzo Di Michele (University of Cambridge, United Kingdom) and Ronit Freeman (University of North Carolina - Chapel Hill, United States)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Prebiotic Chemistry
Discussion Leader: Wilhelm Huck (Radboud University, The Netherlands)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
Joseph Moran (University of Strasbourg, France)
"Nanogeoelectrochemical Protometabolism"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Albert Fahrenbach (University of New South Wales, Australia)
"Embracing Complexity in Prebiotic Chemistry"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Doron Lancet (Weizmann Institute of Science, Israel)
"Darwinian Origin of Life via Systems Chemistry Affords Proficient Protocell Complexification"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Multiphase Active Systems
Discussion Leader: Gonen Ashkenasy (Ben-Gurion University of the Negev, Israel)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Kate Adamala (University of Minnesota, United States)
"Complexity of Life, but not Quite Alive: Synthetic Minimal Cells"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
Neha Kamat (Northwestern University, United States)
"Harnessing Lipid Phase Segregation to Design Membrane Functions"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
Taylor Woehl (University of Maryland, United States)
"Transient Colloidal Crystals Fueled by Electrochemical Reaction Products"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
Lorenzo Di Michele (University of Cambridge, United Kingdom)
"Synthetic Cells from Smart Nucleic-Acid Condensates"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metal–Ligand Coordination Systems
Discussion Leader: Guido Clever (Technical University of Dortmund, Germany)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
Joost Reek (University of Amsterdam, The Netherlands)
"Systems Chemistry in Formation of Coordination Cages and their Use in Catalysis"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Shuichi Hiraoka (The University of Tokyo, Japan)
"Kinetically Controlled Self-Assembly of Metal–Organic Cages in Reversible Reaction Networks"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Jamie Lewis (University of Birmingham, United Kingdom)
"Directing Isomerism in Low-Symmetry Metal–Organic Cages"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Early-Career Investigator Presentations
Discussion Leader: Akif Tezcan (University of California, San Diego, United States)
9:00 am - 9:10 am
Flavio della Sala (University of Manchester, United Kingdom)
"Dissipative Adsorption with a Catalysis-Driven Information Ratchet"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Beatrice Marincioni (University of Groningen, The Netherlands)
"Compartmentalization of an Artificial Cytoskeleton in Motile Water Droplets"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Zoe Ashbridge (University of Amsterdam, The Netherlands)
"Transient Regulation of Catalysis in a Pt2L4 Cage"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Ifigeneia Tsironi (University of New Mexico, United States)
"Reactive Supramolecular Templates Enable the Fuel-Driven Formation of Transient Conductive Hydrophilic Conduits in Water"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Zhiyin Zhang (UC San Diego, United States)
"Design of Light-Responsive Protein Assemblies"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Shoi Sasaki (Keio university, Japan)
"Creation of Giant Vesicles with Balancing Structural Stability and Stimuli-Responsiveness"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
Jiaqi Pei (Pennsylvania State University, United States)
"Coacervates Serve as Hospitable Compartments to Protect RNA from Hydrolysis under Prebiotic Environmental Perturbations: Wet–Dry Cycling"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
Aliye Hazal Koyuncu Cetinkaya (University of Twente, The Netherlands)
"Surface-Driven Chemical Feedback Systems Based on Polylysine"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Grace Maynard (The University of New South Wales, Australia)
"Creating a Proto-Ribosome: Nonenzymatic Catalysis of Aminoacylation Reactions using Coacervates"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Alex Pak (Colorado School of Mines, United States)
"Coarse-Grained Modeling and Simulation of Pleomorphic Assemblies"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Eli Kengmana (Johns Hopkins University, United States)
"Spatial Control over Reactions via Localized Transcription within Membraneless DNA Nanostar Droplets"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Yoshiya Matsubara (University of Chicago, United States)
"Robustness of Collectively Encoded Genomic Information"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Nucleic Acid Systems Chemistry
Discussion Leader: Andrew Turberfield (University of Oxford, United Kingdom)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
Elisa Franco (UCLA, United States)
"Programmable Dynamic Control of Nucleic Acid Condensates"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Francesco Ricci (University of Rome Tor Vergata, Italy)
"Harnessing Complexity with DNA Nanotechnology: Timing Reactions, Sensing Markers, and Moving Objects"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Masahiro Takinoue (Tokyo Institute of Technology, Japan)
"Sequence-Dependent Control of Nonequilibrium Dynamics on Liquid–Liquid Phase Separation Droplets of Nucleic Acids"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Emergent Function from Supramolecular Assemblies, Coacervates, and Protocells
Discussion Leader: Christine Keating (Pennsylvania State University, United States)
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:45 am
Christoph Weber (University of Augsburg, Germany)
"Chemically Active Emulsions: Size Control, Liquid Shells, and Droplet Division"
9:45 am - 9:55 am
Discussion
9:55 am - 10:25 am
Dibyendu Das (Indian Institute of Science Education and Research (IISER) Kolkata, India)
"Feedback-Driven Autonomous Self-Assemblies"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:40 am
Irene Chen (University of California, Los Angeles , United States)
"Keeping It Together: Biomolecular Function in Nanosize Carriers"
11:40 am - 11:50 am
Discussion
11:50 am - 12:20 pm
Dora Tang (University of Saarland / MPI-CBG, Germany)
"Towards Dynamic Protocellular Systems by Controlled Soft-Matter Assembly"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Exploring High-Dimensional Spaces in Chemistry
Discussion Leader: Dezso Horvath (University of Szeged, Hungary)
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
Lauren Zarzar (The Pennsylvania State University, United States)
"Emergent Behaviors of Droplet Systems with Non-Recirprocal Interactions"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
Steve Whitelam (Lawrence Berkeley National Lab, United States)
"Training Neural Networks to Control Molecular Systems"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
Arvind Murugan (University of Chicago, United States)
"Neural Computation through Learned Phase Diagrams"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure