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Tropical Infectious Diseases

Gordon Research Conference

Basic and Clinical Research Strategies for Tackling Tropical Infectious Diseases in a Globalized World

February 2 - 7, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chair

Vice Chair

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Venue

Office Manager: D'Angelina Mbalire

Office Manager Email: renaissancetuscany_sm@grc.org

Office Phone: +3905837691

Application Information

The application deadline for this meeting was January 5, 2025. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Tropical Infectious Diseases GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes a diverse range of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Tropical Infectious Diseases" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Progress in Vaccine Development Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:15 pm	"Tropical Medicine and the Vaccine Sciences to Achieve Global Health Equity"
8:15 pm - 8:25 pm	Discussion
8:25 pm - 8:45 pm	"Can Vaccines Trigger Malaria Elimination?"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:20 pm	"Cryptococcus Vaccines: Progress and Challenges"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Host-Pathogen Interaction Mechanisms and Evasion of Immune System Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:50 am	"Mycobacterium Tuberculosis Type VII Secretion Systems at the Face of Host Immunity"
9:50 am - 10:00 am	Discussion
10:00 am - 10:25 am	Coffee Break
10:25 am - 11:00 am	"ESCRT-Depleted Trypanosoma Cruzi Secretes Reduced Amounts of Extracellular Vesicles, Infects, but Causes Reduced Sequestering of Mast Cells and No Fibroses in Mice"
11:00 am - 11:05 am	Discussion
11:05 am - 11:40 am	"Compartmentalized cAMP Signals in American Trypanosomes"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Infection Induces S Nitrosylation of Mycobacterial PknG Triggers its Secretion"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Host Factor-Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio Cholerae"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
3:00 pm - 4:00 pm	The GRC Power Hour™ The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring. Organizers: and
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Extracellular Vesicles: Pathogenesis and Diagnostics of Infectious Diseases Discussion Leader:
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:40 pm	"Patho-Physiological Roles of Bacterial Membrane Vesicles"
6:40 pm - 6:45 pm	Discussion
6:45 pm - 7:15 pm	"An Extracellular Vesicle Peptide as a Candidate to Control a Lethal Fungal Infection"
7:15 pm - 7:25 pm	Discussion
7:25 pm - 7:55 pm	"Same Species, Different Extracellular Vesicles: Learning from Pathogenic Fungal Models"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Omics Approaches to Understanding Tropical Infectious Diseases Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"The Role of Bioinformatics in Unravelling Direct and Indirect Gene Repression by the Ecdysone Cascade During Mosquito Reproductive Cycle"
9:35 am - 9:40 am	Discussion
9:40 am - 10:05 am	"Decoding Antifungal Resistance in Candida Auris: Multi-Omics Analysis of Laboratory-Adapted Strains"
10:05 am - 10:10 am	Discussion
10:10 am - 10:40 am	Coffee Break
10:40 am - 11:05 am	"Can Diet Override Genetic Resistance to Salmonella Typhimurium Infection?"
11:05 am - 11:10 am	Discussion
11:10 am - 11:30 am	"Proteomics and Multi-Omics Technologies: Next-Generation Biomarkers for Malaria and COVID-19"
11:30 am - 11:35 am	Discussion
11:35 am - 11:55 am	"LeishGEM: Genome-Scale Life Cycle Fitness Phenotyping and Subcellular Protein Localization in Leishmania Mexicana"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"A Genome-Wide Yeast Surface Display Screen to Identify Vaccine Targets for Chagas Disease"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Prospective Immunotherapy and Drug Treatments Discussion Leaders: and
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:30 pm	"Evaluations of Lectin-Fc Fusion Proteins on the Management of Endemic Mycosis"
6:30 pm - 6:40 pm	Discussion
6:40 pm - 7:00 pm	"Developing New Treatments for Chagas Disease"
7:00 pm - 7:05 pm	Discussion
7:05 pm - 7:25 pm	"Immune Profiles of Healing to Inform Host-Directed Therapies: Can These be Generalized to All Forms of Cutaneous Leishmaniasis?"
7:25 pm - 7:30 pm	Discussion
7:30 pm - 7:40 pm	"Human Monoclonal Antibodies Targeting A35 Protect from Death Against Mpox"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	"Identification of Cross-Stage, Cross-Species Malaria CD8⁺ T Cell Antigens"
7:55 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Clinical Research in Infectious Tropical Diseases Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:30 am	"HIV-Associated Cryptococcal Meningitis: Translating Evidence to Practice"
9:30 am - 9:35 am	Discussion
9:35 am - 9:55 am	"TESEO Phase-2 Clinical Trial: New Chemotherapy Regimens and Biomarkers for Chagas Disease"
9:55 am - 10:00 am	Discussion
10:00 am - 10:30 am	Coffee Break
10:30 am - 10:50 am	"Innovation to Foster Elimination: New Therapies for Leishmaniasis"
10:50 am - 10:55 am	Discussion
10:55 am - 11:15 am	"Adaptive Immune Responses to Dengue Virus Infection in Asymptomatic Patients"
11:15 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Studies Towards the Understanding of Trypanosomatid Virulence Factors and the Development of Vaccines for Leishmaniasis and Chagas Disease"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Reconstructing Acute Phase Kinetics of Antibodies Against Dengue Virus to Triage Individuals with High-Risk for Severe Disease"
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Novel Rezolute Plasma Kallikrein Inhibitors Prevent Inflammatory Pathways Associated with Pediatric Cerebral Malarial"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Biology and Vector Control Discussion Leader:
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:30 pm	"Complex I Driven Respiration Determines the Susceptibility of Aedes Aegypti Mosquitoes to Dengue Virus"
6:30 pm - 6:35 pm	Discussion
6:35 pm - 6:55 pm	"Diversity and Interactions Among Triatoma Sanguisuga, Blood-Feeding Sources, Gut Microbiota, and Trypanosoma Cruzi Transmission"
6:55 pm - 7:00 pm	Discussion
7:00 pm - 7:10 pm	"Role of A. Aegypti Proteins in Viral Colonization of the Vector and Transmission to Mammalian Host"
7:10 pm - 7:15 pm	Discussion
7:15 pm - 7:25 pm	"Additional Blood Meals After Infection Increase Fitness of Malaria Parasites and Their Mosquito Host"
7:25 pm - 7:30 pm	Discussion
7:30 pm - 7:40 pm	"Anopheles Gambiae Larvae’s Ability to Grow and Emerge in Water Containing Lethal Concentrations of Clothianidin, Acetamiprid or Imidacloprid is Consistent with Cross-Resistance to Neonicotinoids"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Global Health Emerging and Re-Emerging Infectious Diseases Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:35 am	"New Insights in T. cruzi Infection Therapeutic Approaches"
9:35 am - 9:40 am	Discussion
9:40 am - 10:05 am	"Lassa Fever: The Road Ahead"
10:05 am - 10:10 am	Discussion
10:10 am - 10:40 am	Coffee Break
10:40 am - 11:00 am	"Eisai's Efforts in Tropical Infectious Diseases"
11:00 am - 11:05 am	Discussion
11:05 am - 11:25 am	"The Emerging Outbreaks of Acute Chagas Disease Through the Consumption of Contaminated Food"
11:25 am - 11:30 am	Discussion
11:30 am - 11:40 am	"Understanding Leptospira Interrogans Infection Through the Lens of Nitrogen Metabolism"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	"Crafting Genomic Surveillance Strategies for Chagas Disease and Leishmaniasis."
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	"Intestinal Parasites and Peripheral Eosinophilia in Populations Screened Through Texas Resettlement Programs"
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:25 pm	"NS1 mRNA Vaccine Elicits Humoral and Cellular Immune Response and Induces Protection Against Denv 2 NGC Intracranial Challenge"
12:25 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Keynote Session: Pathogen Glycobiology: Molecular Targets for Chemo and Immunotherapy Discussion Leaders: and
6:00 pm - 6:10 pm	Introduction by Discussion Leader
6:10 pm - 6:50 pm	"Extracellular Glycans of Pathogenic Fungi: Focus on Cryptococcus"
6:50 pm - 7:00 pm	Discussion
7:00 pm - 7:40 pm	"The Transialidase Virulence Factor, as a Vaccine Candidate for Chagas Disease"
7:40 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number R13AI188930. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Tropical Infectious Diseases (GRS) Contribute Financially to This Conference

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Diversity Funding

Financial assistance is available for qualified applicants through the GRC Carl Storm Underrepresented Minority Fellowship Program. This program provides a grant to underrepresented minority graduate students, postdocs, faculty and scientists to help fund their attendance at their first GRC meeting. Learn more.

Registration Fees

Conferee Single Room:

$1,610.00

Conferee Shared Room:

$1,325.00

Conferee Off-Site:

$915.00

Guest Single Room:

$1,420.00

Guest Shared Room:

$1,135.00

Guest Off-Site:

$725.00

Child 4-12 yrs Shared Room:

$568.00

Child 4-12 yrs Off-Site:

$363.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$62.00

Bus Departing:

$62.00

Additional Fee Info

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