Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Virus Structure and Entry
7:40 pm - 8:00 pm
"Structure and Inhibition of the Replication Machinery of Negative Sense RNA Viruses"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Epstein-Barr Virus Entry"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Class II Membrane Fusion Proteins in Viruses and Cells: Implications for Eukaryotic Evolution"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Influenza Virus Capsid Uncoating"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Immune Response to Viral Infection
9:00 am - 9:20 am
"Role of the Virome in Control of Immunity, and Vice Versa"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Immune Evasion Mechanisms by Flaviviruses and Beyond"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Unraveling Nature's Intrinsic and Innate Antiviral Defenses"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Targeting RIG-I for Antiviral Therapy and Vaccine Adjuvant Against RNA Virus Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Mutagenesis of the Zika Virus Genome Defines Regions with Essential Replication and Immune Evasion Functions"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Mechanisms Dictating Cellular Susceptibility and Resistance to Influenza A Virus Infections In Vivo "
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Virus-Host Receptome Characterization for Discovery of Novel Mechanisms of Immunoregulation"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"IFITM3 Restriction of Virus Infection Requires an Amphipathic Helix"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Viral Replication and Persistence
6:00 pm - 6:20 pm
"Evidence for an Actual Cure of a SHIV-Infected Monkey"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Defining the Cellular Factors Regulating Astrovirus Replication"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Long and Short Non-Coding RNAs in KSHV Biology and Pathogenesis"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Breaking Barriers: Viral Infections of Polarized Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Immune Responses to HIV in Mothers and Their Infants"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Cell and Molecular Mechanisms of Alphavirus Pathogenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Bacteriophages to Treat Antibiotic Resistant Bacteria"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Modulation of Cellular Deubiquitinases Alters Macrophage Functions and Blocks Norovirus Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Repurposing Canonical Antiviral Responses to Promote Viral Infection"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Translation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Lytic Gene Products Is Resistant to mTORC1 Inhibition"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Defective Genome Production Tunes Viral Load and Persistence Through RNA Interference Activation in Arthropods"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Delineating Morbillivirus Entry, Dissemination and Transmission by Studying In Vivo Competition of Multicolor Canine Distemper Viruses in Ferrets"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:20 pm
"Viral and Host Determinants of Influenza Virus Transmission"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Structure-Function Analysis of a Signature Multifunctional Herpesvirus Protein"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Viral Adaptation Through Retrotransposition"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Transcriptome-Wide Analysis of Targets of the Influenza RNase PA-X Reveals Specificity for Functional and Structural Classes of RNAs"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"An Unbiased Approach to Evaluate the Contribution of Rapidly Evolving Sites at Antiviral Interfaces"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Viral Noncoding RNAs: More Surprises"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Small RNA Pathways and Arboviral Persistence in Mosquitoes"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Cytomegalovirus Regulation of Membrane Trafficking and Signaling"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"A Speed-Fidelity Trade-Off Determines the Mutation Rate and Virulence of an RNA Virus"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Poliovirus Utilizes Key Components of the Autophagy Pathway While Bypassing Others"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Genetic Dissection of Flaviviridae Host Factors Through Genome-Scale CRISPR Screens"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Mechanisms and Consequences of Intracellular Distribution of Sendai Virus Genome Species"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Genome-Wide Analysis of Influenza Viral RNA and Nucleoprotein Architecture"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Identification of Two Host Enzymes as Entry Factors for Hepatitis C Virus and Plasmodium Sporozoites"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Viral Modulation of Host Immunity
6:00 pm - 6:20 pm
"Evasion of Innate Immune Responses by Viruses"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Identification of Novel Viral and Host Genetic Elements Impacting Coronavirus Pathogenesis"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Comparative Biology of Poxvirus Immune Evasion Genes to Learn About Virus Biology"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Reovirus Abrogates Immunological Tolerance to Orally Fed Antigen"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Identification of a Riplet-Dependent, RIG-I-Independent Antiviral Response Regulated by Hepatitis C Virus"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
9:00 am - 9:20 am
"MCV Small T Antigen and the Mitotic Environment"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"EBV Regulation of Bcl6: Insights into Viral Mediated Lymphomagenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Human Papillomaviruses and DNA Damage Responses"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Targeting Viral Oncogenic Signals"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Role of Retrotransposon Stimulation During Reactivation of Latent Gammaherpesvirus"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Trimethylation of Histone H3 on Lysine 36 Is Required for Productive Replication of HPV-31"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"CRISPR/Cas9 Screens for Synthetic Lethal Targets in EBV-Transformed B-Cells"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"The KSHV Episome-Host Chromatin Synapse: Elucidation of Nanoscale Architecture"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Viral Therapeutics and Vaccines
6:00 pm - 6:20 pm
"Cytotoxic and Immunogenic Mechanisms of Oncolytic Poliovirus"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Pathogenesis and Therapeutic Treatment of the MERS Coronavirus"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"In Vivo Knock-Down of the Herpes Simplex Virus Type 1 Latency-Associated Transcript Reduces Reactivation from Latency"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Exploring the Antiviral Mechanism and Anti-Angiogenic Effects of Raltegravir During Feline Herpesvirus (FHV-1) Infection of Primary Feline Corneal Epithelial Cells"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
General Discussion
7:50 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure