Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Molecular Mechanisms/Structural Biology
7:40 pm - 8:05 pm
"Wnt Signalosome Assembly is Governed by Conformational Flexibility of Axin and AP2 Clathrin Adaptor"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:35 pm
"Molecular Mechanisms of the β-Catenin Destruction Complex"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Molecular Insights into Wnt Ligand-Specific Signaling"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Dissecting Molecular Mechanisms of Wnt/β-Catenin Pathway Activation"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Stem Cell Regulation/Tissue Homeostasis
9:00 am - 9:25 am
"How to Grow a Cytoneme for Contact Mediated Intercellular Communication"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Spatial Mapping of Telocytes along the Crypt-Villus Axis Reveals Functional Zonation in the Intestinal Epithelium"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:40 am
Short Talk Selected from Poster Abstracts
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
"A Revised Model of Tissue Regeneration in the Gut Epithelium"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
Short Talk Selected from Poster Abstracts
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 12:00 pm
Short Talk Selected from Poster Abstracts
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hour™ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Wnt Signaling in Development
7:30 pm - 7:55 pm
"WNT Signaling Dynamics Controlled by KDM5C during Development Influence Cognition"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"From Progenitor to Progeny: How Wnt Signaling Shapes Cell Fate Through Cell Cycle Control"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"GSK3 and Cellular Dormancy: Linking Embryonic Diapause to Cancer Survival"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Wnt Signaling in Cancer and Disease
9:00 am - 9:25 am
"Age- and Dosage-Dependent Effects of Wnt Signaling in Adrenal Cancer"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Interplay of the Clock and Wnt Signaling"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Targeting WNT in Cancer: It’s Complicated"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Unlocking Pancreatic Islet Regeneration by Modulating Rspo1-Wnt signaling"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Late-Breaking Topic
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Beta-Catenin-Independent Signaling
7:30 pm - 7:55 pm
"Wnt PCP Signaling in Development and Regeneration"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"Mechano-Gradients Drive Morphogen-Noise Correction to Ensure Robust Patterning"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Therapeutic Intervention/Manipulation
9:00 am - 9:25 am
"Manipulating Cell Fate with Frizzled Agonists"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Novel Synthetic Wnt Signal Agonists and their Therapeutic Applications"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Targeting the Wnt Signaling Modulator DKK1 for Oncology"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Late-Breaking Topic
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"The Impact of Wnt signaling on the Genome"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
Short Talk Selected from Poster Abstracts
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
Short Talk Selected from Poster Abstracts
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"Condensates across Functions: β-Catenin in Transcription and Cellular Adhesion"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:25 am
"Regulation of CK1-mediated Dishevelled Phosphorylation by DDX3X RNA Helicase"
9:25 am - 9:30 am
Discussion
9:30 am - 9:55 am
"Regulation of WNT9A/FZD9 Signaling Specificity"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
Late-Breaking Topic
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
Late-Breaking Topic
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Short Talk Selected from Poster Abstracts
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
Short Talk Selected from Poster Abstracts
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"Cell Fate Decisions are Controlled by Lysosomal Rewiring of Nutrient Utilization"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"The Role of Wnt/STOP in Drug-Resistant Cancer Cells"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure