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Cytoskeletal Motors (GRS)

Gordon Research Seminar

Molecular Motors and Their Tracks: Biophysics, Physiology, and Disease

July 9 - 10, 2022
Chair

Conference Description

The Gordon Research Seminar on Cytoskeletal Motors is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas. Along with sharing science, it will also focus on career development. This is the first time that the Cytoskeletal Motors GRC will be accompanied by a GRS.

The focus of this meeting is on cytoskeletal motors and their tracks. The scope of topics will include structural and biophysical characterization through cellular and organismal physiology and disease states. We are also interested in cytoskeletal cross talk, and emerging systems for studying motors and their tracks.

Related Meeting

This GRS will be held in conjunction with the "Cytoskeletal Motors" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Understanding the Molecular Basis of Cardiomyopathy
Discussion Leader:
3:45 pm - 4:20 pm
"From Slime Mold to Human Cardiomyopathy: Lessons From Over Five Decades of Research"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Motor Dysfunction and Disease
Discussion Leader:
7:30 pm - 7:45 pm
"An Intracellular Bacterium Hijacks BICD1/2-Dependent Dynein Motility to Evade Autophagy"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Tau Inhibits the Long-Range, Dynein-Mediated Motility of Early Phagosomes"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Mediation of Cisplatin Resistance Through Cis and Trans Effects on Microtubule Dynamics"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Establishing an Experimental Pipeline to Determine Functional Effects of Neurodegenerative Mutations in Kinesin-1"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Molecular Regulatory Mechanisms of Human Myosin 7a"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Allosteric Destabilization of the Super-Relaxed State of Myosin by Hypertrophic Cardiomyopathy-Causing Mutations"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Molecular Motors and Their Tracks
Discussion Leader:
9:00 am - 9:15 am
"Differential Regulation of Astral Microtubules in a Shared Cytoplasm"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"The ß-tubulin Tail Differentially Regulates Budding Yeast Kinesin-5 Motors"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Cryo Electron Microscopy Provides the Model of the Cardiac Myosin Binding Protein-C N-Terminus Interaction with the Thin Filament"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"A Dynein-Lis1 Structure Captures an Intermediate State in Dynein’s Activation Pathway"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Development and Optimisation of a New Single Molecule Assay to Study Kinesin-1 Activation"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"TRAK2 Coordinates Opposing Microtubule Motors for Mitochondrial Transport"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Panel Discussion: Getting a Job (That Is Right for You) and Effective Professional Networking
Discussion Leader:
1:30 pm - 2:30 pm
Panel Discussion
Getting a Job (That Is Right for You) and Effective Professional Networking
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes

Contributors

Gordon Research Seminars
National Science Foundation (NSF)
LUMICKS B.V.
Chroma Technology Corporation

Conference Links

Conference History Cytoskeletal Motors
Additional Fee Info

Cytoskeletal Motors
July 12 - 17, 2026


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