| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | WELCOME AND KEYNOTE LECTURE |
| Lewis Tilney - University of Pennsylvania, Philadelphia, PA
"The Drosophilia bristle: How actin filaments define cell form" |
| 9:00 pm - Midnight | Opening Reception in Ware Campus Center |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ACTIN POLYMERIZATION AND DYNAMICS OF THE LEADING EDGE |
| Discussion Leader: John Condeelis - Albert Einstein College of Medicine, New York, NY |
| 9:00 am - 9:30 am | John Condeelis - Albert Einstein College of Medicine, New York, NY
"Actin nucleation at the leading edge and how it steers carcinoma cells" |
| 9:30 am - 10:00 am | John Hartwig - Brigham and Women's Hospital, Harvard Medical School, Boston, MA
"Adducin at the membrane-cytoskeletal interface" |
| 10:00 am - 10:30 am | Thomas Pollard - Yale University, New Haven, CT
"Regulation of actin assembly by Arp2/3 complex and formins" |
| 10:30 am - 11:00 am | Coffee Break / Photo |
| 11:00 am - 11:30 am | Tanya Svitkina - Northwestern University Medical School, Chicago, IL
"Filopodia: the urge to merge" |
| 11:30 am - 11:45 am | Michael Eck - Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA
"Crystal structure of a formin homology-2 domain" |
| 11:45 am - 12:00 pm | Dyche Mullins - University of California, San Francisco, CA
"Molecular mechanism of Arp2/3 dependent actin nucleation" |
| 12:00 pm - 12:15 pm | Dorothy A. Schafer - University of Virginia, Charlottesville, VA
"Regulating actin dynamics by dynamin2" |
| 12:15 pm - 12:30 pm | Jack Taunton - University of California, San Francisco, CA
"Polarized assembly of an N-WASP network drives vesicle motility" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CELL POLARITY AND DEVELOPMENT |
| Discussion Leader: Lynn Cooley - Yale University, New Haven, CT |
| 7:30 pm - 8:00 pm | Lynn Cooley - Yale University, New Haven, CT
"Joining forces: classical genetics and modern protein expression screens to study the Drosophila cytoskeleton during oogenesis" |
| 8:00 pm - 8:30 pm | Kathy Miller - Washington University, St. Louis, MO
"Myosin VI and regulation of actin dynamics" |
| 8:30 pm - 9:00 pm | Ilan Davis - Wellcome Trust Centre for Cell Biology, University of Edinburgh, United Kingdom
"mRNA localization by Dynein mediated transport in Drosophila embryos and oocytes" |
| 9:00 pm - 9:15 pm | Michael Welte - Brandeis University, Waltham, MA
"A directionality determinant for lipid-droplet movement in Drosophila embryos" |
| 9:15 pm - 9:30 pm | Buzz Baum - Ludwig Institute for Cancer Research, University College London, United Kingdom
"Morphogenesis: A functional genomic approach" |
| 9:30 pm - Midnight | Social in Ware Campus Center |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CYTOSKELETAL CROSS-TALK |
| Discussion Leader: Michael Way - Cancer Research UK, London, United Kingdom |
| 9:00 am - 9:15 am | Michael Way - Cancer Research UK, London, United Kingdom
"Understanding how vaccinia virus switches from microtubule to actin based motility" |
| 9:15 am - 9:45 am | John V. Small - Austrian Academy of Sciences, Salzburg, Austria
"Nanometre targeting of microtubules to focal adhesions" |
| 9:45 am - 10:15 am | Alexander Bershadsky - The Weizmann Institute of Science, Rehovot, Israel
"Aspects of adhesion-dependent regulation of cytoskeletal dynamics" |
| 10:15 am - 10:45 | Erika Holzbaur - University of Pennsylvania, Philadelphia, PA
"Cytoplasmic dynein in axonal transport and cytoskeletal crosstalk" |
| 10:45 am - 11:15 am | Coffee Break |
| 11:15 am - 11:45 am | Chihiro Sasakawa - Institute of Medical Science, Tokyo, Japan
"Exploiting host microtubule dynamics by Shigella: a new aspect of bacterial invasion" |
| 11:45 am - 12:00 pm | Jody Rosenblatt - MRC-Laboratory for Molecular Cell Biology, University College London, United Kingdom
"Cortical actin and myosin are required for centrosome separation during mitotic spindle assembly" |
| 12:00 pm - 12:15 pm | Mark McNiven - The Mayo Clinic, Rochester, MN
"The large GTPase dynamin is required to complete cytokinesis and maintain centrosome integrity" |
| 12:15 pm - 12:30 pm | Vladimir Rodionov - University of Connecticut Health Sciences Center, Farmington, CT
"Centrosome positioning is maintained by opposing forces generated by actomyosin system and cytoplasmic dynein" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MOTORS AND CARGOES |
| Discussion Leader: Margaret Titus - University of Minnesota, Minneapolis, MN |
| 7:30 pm - 8:00 pm | Margaret Titus - University of Minnesota, Minneapolis, MN
"A novel role for M6 in maintaining the asymmetric segregation of organelles" |
| 8:00 pm - 8:30 pm | Joel L. Rosenbaum - Yale University, New Haven, CT
"Intraflagellar transport, its cargoes and cilia-dependent diseases" |
| 8:30 pm - 9:00 pm | Richard Cheney - University of North Carolina, Chapel Hill, NC
"Myosin-X and intrafilopodial motility" |
| 9:00 pm - 9:15 pm | John A. Mercer - McLaughlin Research Institute, Great Falls, MT
"Chemical-genetic sensitization of myosin V" |
| 9:15 pm - 9:30 pm | Laura Megeath -Harvard Medical School and Children's Hospital Boston, MA
"Milton, the mitochondria won't leave soma without it" |
| 9:30 pm - Midnight | Social in Ware Campus Center |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SPINDLE ASSEMBLY AND FUNCTION |
| Discussion Leader: Rebecca Heald - University of California, Berkeley, Berkeley, CA |
| 9:00 am - 9:30 am | Rebecca Heald - University of California, Berkeley, Berkeley, CA
"How chromatin promotes spindle assembly and function" |
| 9:30 am - 10:00 am | David Burgess - Boston College, Boston, MA
"A potential signaling pathway for embryonic cell cytokinesis" |
| 10:00 am - 10:30 am | Patricia Wadsworth - University of Massachusetts, Amherst, MA
"Contribution of non-centrosomal microtubules to spindle assembly in mammalian cells" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Francois Nedelec - EMBL, Heidelberg, Germany
"Computer models of mitotic spindle formation" |
| 11:30 am - 11:45 am | Yves Barral - Institute of Biochemistry, Swiss Federal Institute of Technology (EHT), Zurich, Switzerland
"Spindle asymmetry is required for correct intracellular spindle positioning" |
| 11:45 am - 12:00 pm | Ryoma Ohi - Harvard Medical School, Boston, MA
"An inner centromere protein that stimulates the microtubule depolymerizing activity of a Kinl kinesin" |
| 12:00 pm - 12:15 pm | Gohta Goshima -University of California, San Francisco, CA
"The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line" |
| 12:15 pm - 12:30 pm | Tarun M. Kapoor - The Rockefeller University, New York, NY
"Minus-end capture of pre-formed kinetochore fibers contributes to spindle morphogenesis" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session III |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TRANSIENT CONTRACTILE STRUCTURES |
| Discussion Leader: William Bement - University of Wisconsin, Madison, WI |
| 7:30 pm - 7:55 pm | Yu-Li Wang - University of Massachusetts, Worcester, MA
"Functions of midzone microtubules and midbodies" |
| 7:55 pm - 8:15 pm | Will Wood - University College London, United Kingdom and Instituto Gulbenkian de Ciencia, Oeiras, Portugal
"Tissue repair and morphogenetic movements in embryos" |
| 8:15 pm - 8:40 pm | Michael Glotzer - Research Institute of Molecular Pathology, Vienna, Austria
"Initiation and completion of cytokinesis" |
| 8:40 pm - 9:05 pm | Fred Chang - Columbia University College of Physicians and Surgeons, New York, NY
"Formins in cytokinesis and cell polarity" |
| 9:05 pm - 9:30 pm | William Bement - University of Wisconsin, Madison, WI
"Assembly of transient contractile arrays: Lessons from single cell wound healing" |
| 9:30 pm - Midnight | Social in Ware Campus Center |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | NEURONAL CYTOSKELETON |
| Discussion Leader: Peter Hollenbeck - Purdue University, West Lafayette, IN |
| 9:00 am - 9:30 am | Peter Hollenbeck - Purdue University, West Lafayette, IN
"The regulation of mitochondrial transport in axons" |
| 9:30 am - 10:00 am | Larry Goldstein - UCSD School of Medicine, La Jolla, CA
"Linking molecular motors to signaling and neurodegenerative disease" |
| 10:00 am - 10:30 am | Shelley Halpain - The Scripps Research Institute, La Jolla, CA
"Cytoskeletal mechanisms in neurite initiation" |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:30 am | Yukiko Goda - University College of London, London, United Kingdom
"Regulating actin cytoskeleton and synaptic plasticity" |
| 11:30 am - 12:00 pm | Peter A. Kolodziej - Vanderbilt University Medical Center, Nashville, TN
"E-cadherin controls F-actin and microtubule assembly via distinct sequences in the cytoplasmic domain: a model for guidance receptors?" |
| 12:00 pm - 12:15 pm | Ann Miller - Yale University, New Haven ,CT
"Regulation of the neuronal cytoskeleton by Abl family kinases" |
| 12:15 pm - 12:30 pm | Sergey Popov - University of Illinois at Chicago, Chicago, IL
"Interaction of Tau with microtubules in living cells" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | INFORMAL TUTORIAL ON QUANTITATIVE LIGHT MICROSCOPIC IMAGING AND ANALYSIS TECHNIQUES |
| Discussion Leader: Clare Waterman-Storer - The Scripps Research Institute, La Jolla, CA |
| 4:00 pm - 4:30 pm | Ted Salmon - University of North Carolina, Chapel Hill, NC
"Fluorescent speckle microscopy" |
| 4:30 pm - 5:00 pm | Graham Dunn - King's College London, London, United Kingdom
"Visualizing actin dynamics by FLAP" |
| 5:00 pm - 5:30 pm | Peter Sorger - Massachusetts Institute of Technology, Cambridge, MA
"Image informatics and quantitive analysis of microscope data" |
| 5:30 pm - 6:00 pm | Micah Dembo - Boston University, Boston, MA
"Measuring cellular traction forces with the elastic substrate method" |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MICROTUBULE PLUS END DYNAMICS |
| Discussion Leader: Holly Goodson - University of Notre Dame, Notre Dame, IN |
| 7:30 pm - 8:00 pm | Holly Goodson - University of Notre Dame, Notre Dame, IN
"Mechanism of CLIP-170 microtubule plus-end tracking" |
| 8:00 pm - 8:30 pm | Inke Nathke - University of Dundee, Dundee, United Kingdom
"The adenomatous polyposis coli protein in the cytoskeleton" |
| 8:30 pm - 9:00 pm | Kozo Kaibuchi - Nagoya University, Nagoya, Japan
"Capturing mechanism of microtubule plus ends during cell migration" |
| 9:00 pm - 9:15 pm | Stephen Rogers - University of California, San Francisco, CA
"Drosophila EB1 recruits regulators of cellular morphology and cytoskeletal cross-linkers to the microtubule tip" |
| 9:15 pm - 9:30 pm | Kevin Vaughan - University of Notre Dame, Notre Dame, IN
"Interactions and regulation of microtubule plus-end tracking proteins" |
| 9:30 pm - Midnight | Party in Ware Campus Center |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |
