SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session |
| Discussion Leader: Dennis Discher (University of Pennsylvania) |
7:40 pm - 8:30 pm | Dennis Discher (University of Pennsylvania)
"Matrix elasticity modulates contractility and directs differentiation and de-differentiation processes" |
8:30 pm - 8:50 pm | Discussion |
8:50 pm - 9:10 pm | Matthew J. Paszek (UC San Francisco Medical Center)
"Integrins alone could sense chemical and physical properties of the extracellular matrix" |
9:10 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cell Separation |
| Discussion Leader: David Burgess (Boston University) |
9:00 am - 9:20 am | Bill Sullivan (University of Calif. Santa Cruz) |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | David Burgess (Boston University)
"Control of spindle positioning in dividing sea urchin eggs" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Fred Chang (Columbia University)
"Role of the endoplasmic reticulon in division site placement in cytokinesis" |
10:20 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break / Group Photo |
11:00 am - 11:25 am | Harold Erickson (Duke University)
"FtsZ - cytoskeleton and motor all in one" |
11:25 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Amy Maddox (Institute for Research in Immunology and Cancer, Montreal)
"Anillin is essential for meiotic cytokinesis in C. elegans" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Spatial Regulation of Development and Division |
| Discussion Leader: Meg Titus (Univ. Minnesota) |
7:30 pm - 7:50 pm | Meg Titus (Univ. Minnesota)
"An unconventional myosin required for cell polarization and chemotaxis" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Martin Loose (BIOTEC TU Dresden)
"How molecules make waves: Self-organization of Min proteins in vitro" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Peter Lenart (European Molecular Biology Laboratory - EMBL, Heidelberg)
"The mechanism of actin-driven chromosome congression in starfish oocytes" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Nasser Rusan (UNC-Chapel Hill)
"Drosophila stem cells exhibit asymmetry in centrosome function" |
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cell and Subcellular Orientation |
| Discussion Leader: Gregg Gundersen (Columbia University) |
9:00 am - 9:25 am | Gregg Gundersen (Columbia University)
"Mechanism of actin-dependent nulcear movement during centrosome polarization in migrating cells" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:50 am | Anna Akhmanova (Erasmus Medical Ctr. Rotterdam)
"Regulation of microtubule dynamics by EB proteins and their partners" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Jawdat Al-Bassam (Harvard University)
"The molecular mechanism of Cytoplasmic Linker Associated protein (CLASP) in stabilizing dynamic microtubules" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Ahna Skop (University of Wisconsin)
"Anterior embryonic polarity is maintained by dynamin" |
11:25 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Phong Tran (University of Pennsylvania)
"Motors and MAPs and the Mechanics of Mitosis" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Novel Roles for Cellular Actin |
| Discussion Leader: Yu-Li Wang (Carnigie-Mellon, Pittsburgh) |
7:30 pm - 7:50 pm | Yu-Li Wang (Carnegie-Mellon, Pittsburgh)
"The Mechanism of Cellular Mechanical and Geometry Sensing" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Rong Li (Stowers Institute)
"A pathway of maintaining epithelial organization downstream of the polycystin-mediated fluid stress signaling" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Snezhka Oliferenko (Temasek Life Sciences Laboratory, Singapore) |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Margot Quinlan (UCLA)
"Regulation of the cytoskeleton during Drosophila oogenesis" |
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Organelle and Chromosome Dynamics |
| Discussion Leader: Erika Holzbaur (University of Pennsylvania) |
9:00 am - 9:20 am | Erika Holzbaur (University of Pennsylvania) |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Linda Wordeman (University of Washington)
"Finding the Middle Ground: Motors that influence Chromosome Congression" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Pat Wadsworth (University of Mass. Amherst)
"Eg5/dynein antagonism during bipolar spindle formation requires overlapping centrosomal microtubules" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Iva Tolic-Norrelykke (Max Planck Institute of Molecular Cell Biology and Genetics, Dresden)
"Nuclear centering in fission yeast mediated by kinesin-8 proteins" |
11:25 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | David Pellman (DFCI Harvard U)
"Centrosomes and the Origin of Chromosome instability" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | Polymer Dynamics |
| Discussion Leader: Alexi Khodjakov (Wadsworth Ctr, Albany, NY) |
7:30 pm - 7:50 pm | Alexi Khodjakov (Wadsworth Ctr, Albany, NY)
"Of Kinetochores and Centrosomes" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Dan Fletcher (University of California, Berkeley)
"Force microscopy of actin networks: coupling mechanics and growth" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | David Odde (University of Minnesota)
"Microtubule Assembly Dynamics During Cell Polarization" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Sophie Dumont (Harvard University)
"Mechanical force regulates mitotic spindle size by a mechanochemical switch at the poles" |
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of Chromosome Movement |
| Discussion Leader: Trisha Davis (University of Washington) |
9:00 am - 9:20 am | Trisha Davis (University of Washington)
"The Ndc80 and Dam1 complexes: Attachment to the dynamic end of microtubules" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Maria Schumacher
"Structural mechanisms of plasmid DNA segregation" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Susana A. Ribeiro (University of Edinburgh)
"Condensin regulates the stiffness of the vertebrate centromere" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Duane Compton (Dartmouth University)
"Deviant kinetochore-microtubule dynamics underlies chromosomal instability in cancer cells" |
11:25 am - 11:45 am | Discussion |
11:45 am - 12:10 pm | Ted Salmon (University of North Carolina)
"Molecular Architecture of the Mammalian Kinetochore" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of Motor Proteins |
| Discussion Leader: Enrique de la Cruz (Yale University) |
7:30 pm - 7:50 pm | Enrique de la Cruz (Yale University)
"Everything I need to know about helicases, I learned from myosin" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Trina A. Schroer (Johns Hopkins Univ)
"Identification of a membrane-binding domain of dynacti" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Jon Scholey (University of California, Davis)
"Prometaphase spindle maintenance by antagonistic sliding motors: Factors required for a robust steady state" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | François Nédélec (EMBL)
"Chromatin shapes the Xenopus spindle" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |