SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Presentations: Dynamic Approaches to the Cytoskeleton |
| Discussion Leader: Erika Holzbaur (University of Pennsylvania) |
7:40 pm - 8:20 pm | David Drubin (University of California, Berkeley)
"Harnessing actin dynamics for endocytic trafficking"
|
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Tony Hyman (Max Planck Institute for Cell Biology and Genetics, Dresden)
"Phase separation in cytoplasm"
|
9:15 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cytoskeletal Dynamics |
| Discussion Leader: Peter Rubenstein (University of Iowa) |
9:00 am - 9:20 am | Tom Pollard (Yale University)
"Quantitative analysis of actin dynamics in fission yeast"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Sophie Martin (Universite de Lausanne)
"Yeast polarization strategies for division and mating"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Anna Akhmanova (Utrecht University)
"Functional analysis of microtubule end-binding proteins"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Jenny Ross (University of Massachusetts, Amherst)
"Microtubule severing enzymes control microtubule dynamic instability"
|
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Michael Greenberg (University of Pennsylvania)
"Structural and mechanical insights into the mechanism of myosin-I force sensing"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Grant Jensen (Caltech)
"Type-6 secretion systems and ESCRT: two different machines that drive motion using stored conformational energy"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Building complex structures and long-range organization |
| Discussion Leader: John Cooper (Washington University in St. Louis) |
7:30 pm - 7:50 pm | Tanya Svitkina (University of Pennsylvania)
"Cytoskeletal architecture of specialized cellular structures"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Laurent Blanchoin (Institute of Life Sciences Research and Technologies,
Grenoble, France)
"Directed actin self assembly and contractility"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Irina Kaverina (Vanderbilt University)
"Role of Golgi-derived microtubules in Golgi organization and inheritance in proliferating cells" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Frank Bradke (German Center for Neurodegenerative Diseases)
"Cytoskeletal mechanisms of axonal growth and regeneration" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Posters and Social Session |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Dividing a Cell |
| Discussion Leader: Patricia Wadsworth (University of Massachusetts, Amherst) |
9:00 am - 9:20 am | Helder Maiato (instituto de Biologia Molecular e Celular)
"Functional coordination between kinetochore and arm motors explains chromosome congression in humans"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Chip Asbury (University of Washington)
"New strategies for uncovering how chromosomes are segregated during mitosis"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Group Photo / Coffee Break |
10:30 am - 10:50 am | Buzz Baum (MRC Laboratory for Molecular Cell Biology)
"The mitotic actin cortex"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Mike Lampson (University of Pennsylvania)
"Chromosome segregation in meiosis: violations of Mendel's First Law"
|
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Fred Chang (Columbia University)
"Role of the contractile ring in fission yeast cytokinesis"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Jawdat Al-Bassam (University of California, Davis)
"Tubulin cofactors form multi-subunit machines that regulate tubulin active state and promote microtubule polymerization"
|
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Intracellular dynamics: movement of motors, organelles and cargos |
| Discussion Leader: Vladimir Gelfand (Northwestern University) |
7:30 pm - 7:50 pm | Susan Gilbert (Rensselaer Polytechnic Institute)
"Kinesins: How the ATPase cycle modulates function"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Sam Reck-Peterson (Harvard University)
"Regulation of cytoplasmic dynein"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Roop Mallik (Tata Institute)
"Lipid droplet dynamics in the liver"
|
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Simon Bullock (MRC Cambridge)
"Shedding light on mRNA transport mechanisms in vitro"
|
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Posters and Social Session |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cytoskeletal Dynamics: Insights from bacteria, parasites, fungi, and plants |
| Discussion Leader: Fred Chang (Columbia University) |
9:00 am - 9:20 am | Dyche Mullins (University of California, San Francisco)
"Dynamics of actin and actin-like proteins"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | David Sept (University of Michigan)
"Structure/function differences in parasite actin" |
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Gero Steinberg (University of Exeter)
"Long-range motility of dynein in the model fungus Ustilago maydis" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Magdalena Benzanilla (University of Massachusetts, Amherst)
"Class VIII myosins participate in division site specification" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Ram Dixit (Washington University in St. Louis)
"Understanding how a kinesin contributes to plant cell wall assembly" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | Marija Zanic (Max Planck Institute of Molecular Cell Biology)
"Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levels" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Forces and dynamics in cell biology |
| Discussion Leader: Michael Ostap (University of Pennsylvania) |
7:30 pm - 7:50 pm | Marileen Dogterom (FOM Institute AMOLF)
"Microtubule-based organization in vitro"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Melissa Gardner (University of Minnesota)
"Evolving tip structures can explain age-dependent microtubule catastrophe"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Yale Goldman (University of Pennsylvania)
"New approaches to the biophysics of molecular motors in vitro and in live cells"
|
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Sophie Dumont (University of California, San Francisco)
"Spindle forces for chromosome movement"
|
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Posters and Social Session |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Cells in context: cytoskeletal-matrix connections |
| Discussion Leader: Alpha Yap (University of Queensland) |
9:00 am - 9:20 am | Bill Brieher (University of Illinois, Urbana-Champaign)
"Actin assembly at cadherin adhesive junctions"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Kris DeMali (University of Iowa)
"Mechanisms governing force generation at cell-cell and cell-matrix adhesions"
|
9:50 am - 10:00 am | Discussion |
10:00 am | Coffee Break |
10:30 am - 10:50 am | Scott Crawley (Vanderbilt University)
"Protocadherins regulate the assembly of the actin-rich enterocyte brush border"
|
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Maxence Nachury (Stanford University)
"In vitro reconstitution of ciliary entry" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Manuel Thery (CNRS/CEA/INRA/Université Joseph Fourier)
"Force scaling in stress fibers" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:20 pm | John Condeelis (Albert Einstein College of Medicine)
"Signaling, adhesion and protrusion assembly pathways that define tumor cell behavior in vivo" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Cells on the move |
| Discussion Leader: Bill Bement (University of Wisconsin) |
7:30 pm - 7:50 pm | Denis Wirtz (Johns Hopkins University)
"The perinuclear actin cap in nuclear shaping and cell migration"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | David Sharp (Albert Einstein College of Medicine)
"Cell motility and wound healing"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Matthieu Piel (CNRS)
"Moving under confinement: how immune cells can squeeze their nucleus through tiny holes"
|
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Bill Bement (University of Wisconsin)
"Meeting wrap-up"
|
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Posters and Social Session |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |