Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Cytoskeletal Ensembles Across Scales and Dimensions
7:40 pm - 8:25 pm
"Mechanisms of Mitosis and Size Control in Xenopus "
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Actin-Driven Endocytosis: Below 10 Seconds and Under the Diffraction Limit"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Architecture Dependence of Actin Assembly and Disassembly"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emergent Properties in Two Dimensions: Complex Behaviors in the Cell Cortex and Cortex Models
9:00 am - 9:20 am
"Cellular Form: The Basis of Healthy Function"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Cleavage Furrow Organization in Xenopus Eggs and Extract"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"The Structure of Melanoregulin Reveals a Role for Cholesterol Recognition in the Protein's Ability to Promote Dynein Function"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"An Excitable Cortex Is an Adaptive Trait to Optimize Egg Size and Developmental Time to Larval Body Plan"
10:25 am - 10:30 am
Discussion
10:30 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Active Matters: Probing Forces, Fluctuations and Self-Organization in Actin Cortices"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"Drosophila Syncytial Cleavage Furrows Require an Actomyosin Scaffold Patterned by Circumferential Displacement and Myosin Phospho-Regulation"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Positive Feedback Between the Contractile Ring and the Cell Cortex Drives Cytokinesis"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Phase Separation Enhances Arp2/3 Complex-Dependent Actin Polymerization by Increasing the Membrane Dwell Time of N-WASP"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Active Stress Coordinates Steady States and Contractile Flows in Actomyosin Networks"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
Power Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Corralling Forces, Signals and Targets During Cell Division
7:30 pm - 7:50 pm
"Cell Division: Mechanical Integrity with Dynamic Parts"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Septin Ring in Budding Yeast: How and Why"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Chromosome Bridge Resolution Requires Mechanical Forces from Actin-Based Contractility"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Making and Breaking Kinetochore-Microtubule Attachments in Mitosis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Actin and Microtubules Cooperate to Capture Chromosomes in the Large Oocyte Nucleus"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emergent Properties in One Dimension: Mechanisms that Bestow Sophistication upon Motors and Polymers
9:00 am - 9:20 am
"Molecular-Scale Microtubule Interactions with the α-Tubulin Acetyltransferase Enzyme αTAT1 Alter Cellular-Scale Acetylation Selectivity"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Effects of Nucleotide, Polymerization and Mutation on Actin Structure"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
"Structural Mechanism of a Force-Sensitive Myosin"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"She1 Affects Dynein Motility Through Simultaneous Interactions with the Microtubule and the Dynein Microtubule-Binding Domain"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:20 am
"Nanometer-Scale Mechanisms for Controlling Micron-Scale Coordination and Changes in Actin and Microtubule Networks"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Biochemical Characterization of Actin Assembly by the Drosophila Formin Fhod"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Control of Cargo Specificity for Cytoplasmic Dynein"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"How a Short Collection of Treadmilling Tubulin-Like Filaments Control Bacterial Cell Division"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Bidirectional Interactions of Membranes and the Cytoskeleton
7:30 pm - 7:50 pm
"Tuning of Golgi-Derived Microtubule Nucleation on a Scale of Seconds, Minutes, and Days"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Harnessing Actin Dynamics for Endocytic Trafficking"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Direct Coupling of the Actin Cytoskeleton to a Viral Fusogen Drives Cell-Cell Fusion"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Those Mythterious MyTH4 Myosins: Evolutionary Insights Drawn from Comparisons of Their Roles in Amoebae and Mammals"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Actin Effects Across Two Membranes: How the Formin INF2 Stimulates both Inner and Outer Membrane Dynamics During Mitochondrial Fission"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Coordination of Complex Processes by Signaling and the Cytoskeleton
9:00 am - 9:20 am
"Anillin Regulates Epithelial Mechanics by Structuring Junctional and Medial-Apical Actin Networks"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"CARMIL3's Role in Establishing Left-Right Asymmetry During Zebrafish Development"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Actin Stability Promotes Stress Resistance in Morphogenesis"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"The Frog-Killing Chytrid Fungus Is a Naked Amoeba that Can Build a Cell Wall"
10:15 am - 10:20 am
Discussion
10:20 am - 10:40 am
"Supergrowth: Coordination of Cell Growth with Cell Size, Cytoplasmic Density and Turgor Pressure"
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
Coffee Break
11:10 am - 11:20 am
"Optogenetic Regulation of Rho1 in Drosophila "
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Mechanochemical Signaling at the Adherens Junction"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Processive Motility of Multi-Motor Kinesin-14 Teams Underlies Regulation of Microtubule Minus-End Dynamics"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Dynamic Force Patterns Coordinate Cell Movements During Embryonic Wound Repair"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Septum Formation in Fission Yeast Cytokinesis"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Modeling and Measuring Mesoscopic Cytoskeletal Rearrangements in Cytokinesis"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Actin-Like Protein FtsA Self-Organizes to Reshape Membrane Architecture and Remodel the Z-Ring in Escherichia coli "
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"FLIRTing with Cytokinesis: Testing Cell Division Models Using Local Inactivation of Cytokinetic Proteins"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"New Mechanistic Insights About Cytokinesis in Fission Yeast"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Divergent Dynamics and Behaviors of Cytoskeletal Ensembles
9:00 am - 9:20 am
"Torques and Forces in the Mitotic Spindle"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"The Evolutionary Basis of Microtubule Quaternary Structure"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"One Centriole for Each Occasion - Centriole Variation in Development, Evolution and Disease"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"The ESCRT-III Machinery of Cytokinetic Abscission Is Spatio-Temporally and Functionally Linked to Septin GTPases"
10:15 am - 10:20 am
Discussion
10:20 am - 10:40 am
"Reeling in the Cilium: How Chytrid Fungi Rapidly Retract a Long Ciliary Axoneme into the Cell Body"
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
Coffee Break
11:10 am - 11:20 am
"Rab27a Co-Ordinates Actin-Dependent Long-Range Organelle Transport by Integrating the Activity of Motors and Track Assembly Proteins"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Molecular Insight into Microtubule Nucleation"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Design Principles of a Microtubule Polymerase"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Probing ESCRT-III Filament Dynamics at Different Scales"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
On the Mechanisms of Cells Moving and Sitting Still
7:30 pm - 7:50 pm
"A Template for Actin Organization at the Leading Edge"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Intracellular Calcium and Actin Polymerization Are Antagonistic During Polarized Cell Expansion"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Feedbacks Between ECM Signaling, GTPase Signaling, and Cytoskeletal Remodeling Promote Morphological Heterogeneity Among Motile Cells"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Molecular-Scale Anisotropy and Orientation of Activated Integrins in Focal Adhesions Due to Retrograde Actin Flow"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Cooperation of Nonmuscle Myosin Paralogs in Cell-Wide Organization of the Actin Cytoskeleton"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure